老年心血管危险因素与动脉硬化的相关性研究:北上海社区老年人心血管病研究  

Association of Arterial Stiffness with Cardiovascular Risk Factors:the Northern Shanghai Study

作　　者：许津[1] 秦艳莉[1] 王凯[1] 吕煜焱 熊婧[1] 白彬[1] 于世凯[1] 周益武 迟琛 张毅[1] 徐亚伟[1] 

机构地区：[1]同济大学附属第十人民医院心内科,上海200072

出　　处：《中国循证医学杂志》2016年第12期1365-1369,共5页Chinese Journal of Evidence-based Medicine

基　　金：上海市卫计委重要疾病联合攻关重大项目资助(编号:2013ZYJB0902)

摘　　要：目的探讨老年人群中心血管危险因素与动脉硬化之间的关系。方法自2014年7月至2015年8月,在北上海10个社区纳入1 599名老年居民(年龄≥65岁)。采用Sphygmo Cor动脉硬化检测仪检测患者颈-股脉搏波传导速度(cf-PWV)。心血管危险因素采用问卷、体格检查或标准检测方法获得。采用SPSS 20.0统计软件包进行统计分析。结果 cf-PWV与高龄、肥胖、高血压、糖尿病、脂质代谢异常等心血管危险因素均呈显著相关性(P<0.001)。而且,随着心血管危险因素个数的累积,cf-PWV呈逐渐上升的趋势。这种趋势在全部人群、男性及女性中均达到了统计学显著性标准(P<0.001)。结论动脉硬化的进展与高龄、肥胖、高血压、糖尿病、脂质代谢异常等心血管危险因素的累积紧密相关。Objective To investigate the association of arterial stiffness with cardiovascular risk factors. Methods From July 2014 to August 2015, 1 599 participants aged over 65 years old were recruited from 10 communities located in the northern Shanghai. Carotid-femoral pulse wave velocity （cf-PWV） was measured by SphygmoCor device. Cardiovascular risk factors were assessed by questionnaire, anthropometry or conventional biochemical measurements. SPSS 20.0 was applied for data management and statistical analysis. Results Cf-PWV was significantly associated with cardiovascular risk factors （P〈0.001）. Moreover, with the accumulating cardiovascular risk factors, cf-PWV increased gradually and significantly （P〈0.001）. The increasing trend remained significant in all participants, in men and in women, respectively. Conclusion Arterial stiffness is significantly associated with cardiovascular risk factors and their accumulation.

关 键 词：老年人 动脉硬化 心血管危险因素 脉搏波传导速度 人群研究 

分 类 号：R543.5[医药卫生—心血管疾病]