妊娠高血压疾病眼底病变患者对比敏感度变化情况  

Contrast sensitivity analysis about fundus changes of hypertensive disorders complicating pregnancy

作　　者：王志学[1] 王文英[1] 韩风梅[1] 

机构地区：[1]沧州市中心医院眼科,河北沧州061000

出　　处：《中南大学学报（医学版）》2016年第11期1215-1219,共5页Journal of Central South University ：Medical Science

摘　　要：目的:观察妊娠高血压疾病患者矫正视力及对比敏感度情况。方法:98例妊娠高血压疾病患者进行矫正视力,眼底检查及空间敏感度为1.5,3.0,6.0,12.0,18.0 c/d时的对比敏感度检测。正常对照组选取同期在产科门诊就诊的孕妇50例。妊娠高血压疾病患者与正常对照组患者矫正视力及对比敏感度比较采用两独立样本t检验;妊娠高血压疾病患者矫正视力与对比敏感度之间的相关性采用spearman相关性检验。比较眼底早期患者与眼底晚期患者的对比敏感度情况。结果:妊娠高血压疾病患者矫正视力及对比敏感度均比正常对照组降低(P<0.01)。妊娠高血压疾病患者矫正视力与对比敏感度各个空间频率均相关(P<0.01),其中矫正视力与空间频率为6.0 c/d时的相关性最大(r=0.87)。眼底病变晚期患者比早期患者各空间频率对比敏感度均下降(P<0.01)。结论:妊娠高血压疾病患者矫正视力及对比敏感度均降低,晚期眼底病变对比敏感度下降更明显,矫正视力与空间频率为6.0 c/d时的对比敏感度相关性最大。对比敏感度可比视力检查更全面地评估妊娠高血压患者视网膜功能受损的情况。Objective： To observe corrected visual acuity and contrast sensitivity（CS） in patients with hypertensive disorders complicating pregnancy accompanied by fundus changes.Methods： Ninety-eight patients with hypertensive disorders complicating pregnancy and 50 healthy pregnant women underwent eye examination, including corrected visual acuity and fundus examination, and CS. Differences in corrected visual acuity and contrast sensitivity between the 2 groups were analyzed with two independent samples t-test analysis, while correlation between vision and contrast sensitivity in patients was evaluated by using spearman correlation test. Diff erence in CS was compared between the early and advanced stage of fundus diseases.Results： Corrected visual acuity and contrast sensitivity in patient with hypertensive disorderscomplicating pregnancy were lower than that in the control group（P〈0.01）. Corrected visual acuity in patients was associated with contrast sensitivity at variously spatial frequencies（P〈0.01）, showing the most correlation in contrast sensitivity at 6 of spatial frequency（r=0.87）. Compared with the early stage, the CS in the advanced patients with fundus diseases was decreased（P〈0.01）.Conclusion： The visual acuity and contrast sensitivity in patient with hypertensive disorders complicating pregnancy are reduced. The CS（6.0 c/d） has the largest correlation with corrected visual acuity. Comparing with the visual acuity, contrast sensitivity can be more comprehensive in evaluation of retinal function damage in patients with hypertensive disorders complicating pregnancy.

关 键 词：妊娠高血压疾病 视网膜病变 对比敏感度 矫正视力 空间频率 

分 类 号：R714.246[医药卫生—妇产科学]