硼氢化钠促进下的药物分子制备  

Sodium Borohydride Promotes Drug Molecules Preparation

作　　者：汪泽洋 卢松[1] 浮燕[1] 王辉[1] 赵冠男[1] 

机构地区：[1]空军勤务学院航空四站系,江苏徐州221000

出　　处：《山东化工》2016年第23期29-32,共4页Shandong Chemical Industry

摘　　要：硼氢化钠是一种还原性能优良的"万能还原剂",其常用于多种有机官能团的还原,如醛、酮等物质,而经过修饰的硼氢化钠在还原领域的应用也越来越多的被发现。在一定的还原体系下,硼氢化钠还原时具有较好还原性,如酰胺、酰氯的还原。另一方面,由于硼氢化钠较高的储氢量,温和的反应条件,使得它成为了人们研制"绿色能源"氢气的热门原料,故而有很多的催化制氢的催化剂被研究出来,也有人发现了复合硼氢化钠制氢的优点。Sodium borohydride reduction is an excellent performance of ＂universal reducing agent＂, which commonly used in a variety of reduction of organic functional groups, After the modified sodium borohydride reduction was greatly expanded in the field of application, can be used to restore the carboxylic acids, carboxylic acid esters, alcohols, indole, enyne other substances, under certain reduction system,when compared with a sodium borohydride reduction good reduction. On the other hand, due to the high amount of sodium borohydride hydrogen storage, mild reaction conditions, making it the people developed ＂green energy＂ hot hydrogen raw materials, and therefore there are many catalytic hydrogen production catalysts are finding out, it was discover the advantages of composite sodium borohydride hydrogen production.

关 键 词：硼氢化钠 还原 药物分子 

分 类 号：TQ131.1[化学工程—无机化工]