反应性壳聚糖季铵盐的抗菌性能及其在桑蚕丝织物后整理中的应用  

Antibacterial property of reactive chitosan quaternary ammonium salt and its application in the finishing of silk fabric

作　　者：张伟[1] 戴新兰[2] 周静洁[2] 朱刚 徐洵 黄颖霞[1] 王笃杰[1] 

机构地区：[1]盐城工学院纺织服装学院,江苏盐城224051 [2]江苏出入境检验检疫局纺织实验室,江苏南京225300 [3]苏州市有冠泰纺织品有限公司,江苏苏州215228

出　　处：《印染助剂》2016年第12期41-44,共4页Textile Auxiliaries

基　　金：江苏省产学研前瞻性联合创新资金研究项目(BY2016065-56);盐城市农业项目(YKN2015006)

摘　　要：将壳聚糖与2,3-环氧丙基三甲基氯化铵反应,合成2-羟丙基三甲基氯化铵壳聚糖(HTCC),再将HTCC与N-羟甲基丙烯酰胺反应,合成带有纤维反应性基团的水溶性O-甲基丙烯酰胺壳聚糖季铵盐(NMA-HTCC)。采用最小抑菌质量浓度法测定并比较了壳聚糖及NMA-HTCC的抗菌性,并将其用于桑蚕丝织物的抗菌整理,采用振荡烧瓶法对处理前后的丝织物进行抗菌性测试。结果表明,壳聚糖及NMA-HTCC对金黄色葡萄球菌和大肠杆菌均有显著的抑菌性,且NMA-HTCC的抑菌效果优于壳聚糖;经壳聚糖及NMA-HTCC处理后,桑蚕丝织物对金黄色葡萄球菌和大肠杆菌的抑菌率均明显提高,且NMA-HTCC的抑菌效果更好。将NMA-HTCC改性桑蚕丝织物作为药物载体,对芦荟蒽醌化合物具有良好的缓释效果。2-Hydroxypropyl trimethyl ammonium chloride chitosan （HTCC） was synthesized with chitosan and 2,3-epoxypropyl trimethyl ammonium chloride. Then the water soluble O-methyl acrylamide chitosan qua- ternary ammonium salt （NMA-HTCC） containing fiber reactive groups was synthesized with HTCC and N-methylolacrylamide. The antibacterial activity of chitosan and NMA-HTCC were determined by the mini- mum inhibitory concentration method, and the comparison was carried out. Chitosan and NMA-HTCC were used in the antibacterial finishing of mulberry silk fabric, and the antibiotic resistance of silk before and after the treatment was tested by flask shaking method. The results showed that both chitosan and NMA-HTCC had significant antibacterial activity against Staphylococcus aureus and Escherichia coli, and the antibacterial activity of NMA-HTCC was better than that of chitosan. The antibacterial activity of silk fabric, which was treated by chitosan and NMA-HTCC, to Staphylococcus aureus and Escherichia coli were significantly improved, and the anti- bacterial activity of the silk fabric finished by NMA-HTCC was better than that of silk fabric finished by chito- san. The NMA-HTCC modified silk fabric had good slow-release performance to aloe anthraquinones extract when used as a drug carrier.

关 键 词：反应性壳聚糖季铵盐 抗菌 桑蚕丝 芦荟蒽醌 缓释 

分 类 号：TQ610.42[化学工程—精细化工]