胰岛素泵治疗对2型糖尿病合并妊娠产妇血糖控制及新生儿的影响观察  

Observation on the effect of insulin pump therapy on blood glucose control of the patients with type 2 diabetes mellitus complicated with pregnancy and their neonates

作　　者：庞雅玲[1] 杨丽华[1] 

机构地区：[1]陕西省人民医院,陕西西安710068

出　　处：《中国妇幼保健》2016年第24期5501-5503,共3页Maternal and Child Health Care of China

摘　　要：目的研究胰岛素泵治疗对2型糖尿病合并妊娠产妇血糖控制及新生儿的影响。方法选取陕西省人民医院2014年8月-2016年5月收治的2型糖尿病合并妊娠产妇100例,采用随机数字表法将100例2型糖尿病合并妊娠产妇分为观察组(50例)和对照组(50例)。对照组采取皮下胰岛素注射治疗,观察组采用胰岛素泵治疗。观察对比两组患者的血糖控制情况、胰岛素分泌指数(HOMA-β)、胰岛素抵抗指数(HOMA-IR)、妊娠并发症以及新生儿并发症。结果观察组的空腹血糖、餐后2 h血糖以及糖化血红蛋白均优于对照组(P<0.05);观察组的HOMA-β与HOMA-IR均优于对照组(P<0.05);观察组产妇的并发症发生率为36.00%,与对照组(64.00%)比较,差异有统计学意义(P<0.05);观察组产妇分娩的新生儿并发症发生率为12.00%,与对照组(30.00%)比较,差异有统计学意义(P<0.05)。结论胰岛素泵能够有效地控制2型糖尿病合并妊娠产妇的血糖水平,减少了多次皮下注射的痛苦,产妇以及新生儿并发症较少,值得进一步推广。Objective To research the effect of insulin pump therapy on blood glucose control of the patients with type 2 diabetes mellitus complicated with pregnancy and their neonates. Methods One hundred patients with type 2 diabetes mellitus complicated with pregnancy were selected from the hospital from August 2014 to May 2016,then they were divided into observation group（50 patients） and control group（50 patients）; the patients in control group were treated by subcutaneous injection of insulin,and the patients in observation group were treated by insulin pump. Blood glucose control situations,insulin secretion index（ HOMA- β）,insulin resistance index（ HOMA-IR）,pregnancy complications,and neonatal complications in the two groups were compared. Results Fasting blood glucose,2- hour postprandial blood glucose,and glycosylated hemoglobin in observation group were statistically significantly better than those in control group（ P〈0. 05）; HOMA- β and HOMA- IR in observation group were statistically significantly better than those in control group（ P〈0. 05）; the incidence rates of maternal complications in observation group and control group were 36. 00% and 64. 00%,respectively,there was statistically significant difference between the two groups（ P〈0. 05）; the incidence rates of neonatal complications in observation group and control group were 12. 00% and 30. 00%,respectively,there was statistically significant difference between the two groups（ P〈0. 05）. Conclusion Insulin pump can effectively control blood glucose of patients with type 2 diabetes mellitus complicated with pregnancy and reduce the pain of subcutaneous injection,maternal and neonatal complications are few,the mthod is worthy of further promotion.

关 键 词：胰岛素泵 2型糖尿病 产妇 血糖控制 新生儿 

分 类 号：R714.256[医药卫生—妇产科学]