CT阻塞指数对肺栓塞的评价及其与D-二聚体相关性分析  

Assessing the severity of acute pulmonary embolism using CT obstruction index and the relationship between its CT obstruction index and D-dimer levels

作　　者：杨喜彪 卢春燕[1] 许昭敏 肖云华 张洪静 易群[5] 白红利[1] 

机构地区：[1]四川大学华西医院放射科 [2]重症医学科 [3]呼吸内科,四川成都610041 [4]重庆市渝北区人民医院放射科 [5]四川大学华西第四医院放射科

出　　处：《实用放射学杂志》2016年第12期1876-1879,共4页Journal of Practical Radiology

摘　　要：目的：探讨肺动脉CT阻塞指数对肺栓塞（PE）高危性的评价及其与D-二聚体之间的关系。方法收集经 CT肺动脉成像（CTPA）及D-二聚体检查的125例PE病例。将其分为高危PE组和非高危PE组,比较分析2组在 CT阻塞指数、D-二聚体、主肺动脉直径间的差异,以及肺动脉 CT 阻塞指数与 D-二聚体、主肺动脉直径之间的相关性（Spearman相关性评价）。结果高危PE组的CT阻塞指数明显高于非高危PE组（P=0.000）,高危PE组主肺动脉直径较非高危PE组增粗,差异有统计学意义（P=0.000）,而高危PE组和非高危PE组D-二聚体差异无统计学意义（P=0.103）。CT阻塞指数与D-二聚体无相关性（P=0.71）。结论血浆D-二聚体指标可以提示PE,不能评价PE的高危性；肺动脉CT阻塞指数在一定程度上可以反映PE的严重性,其与 D-二聚体间无相关性。Objective To assess the value of pulmonary artery CT obstruction index for the evaluation of the severity of pulmonary embolism （PE）,and to investigate the relation between pulmonary artery CT obstruction index and D-dimer levels.Methods 125 patients were diagnosed as PE by computed tomographic pulmonary angiography （CTPA）and D-dimer.Patients were separated into high-risk group and non-high risk group.CT obstruction index,D-dimer levels,diameter of the pulmonary artery were compared between two groups. Spearman’s rank correlation coefficients were used to assess the correlation between the CT obstruction index and the D-dimer levels,diameter of the pulmonary artery.Results CT congestion index of high-risk PE group was obviously higher than that of the non-high risk group （P=0.000）.The diameter of pulmonary artery in high-risk PE group was obviously greater than that of the non-high risk group,the difference was statistically significant （P=0.000）.No statistically significant difference was found in D-dimer levels between the two groups （P=0.103）.There was no correction with CT congestion index and D-dimer levels（P=0.71）.Conclusion The D-dimer levels of serum was a predictor of pulmonary embolism,cannot evaluate the severity of PE.CT obstruction index can reflect the severity of PE in some extent as an indicator of PE,there was no correlation with CT obstruction index and D-dimer levels.

关 键 词：肺栓塞 阻塞指数 D-二聚体 计算机体层成像 血管造影术 

分 类 号：R563.5[医药卫生—呼吸系统] R814.42[医药卫生—内科学]