MR功能成像对早期强直性脊柱炎骶髂关节的定量评估  

Quantitative analysis of early ankylosing spondylitis sacroiliac joint by multiple functional MR imaging

作　　者：刘玉涛[1] 洪国斌[2] 周盼妍 梁建超[1] 杜中立[1] 李淑明[1] 安涛[1] 李文娟[2] 

机构地区：[1]珠海市人民医院放射科,广东珠海519000 [2]中山大学附属第五医院放射科

出　　处：《实用放射学杂志》2016年第12期1915-1918,共4页Journal of Practical Radiology

基　　金：国家自然科学基金资助项目（81271561）;珠海市科技计划项目（2015A1023）.

摘　　要：目的：探讨联合应用T2＊mapping T2＊值和扩散加权成像（DWI）的表观扩散系数（ADC）值定量评估骶髂关节炎性活动性的可行性。方法将30例强直性脊柱炎（AS）根据病情严重程度按临床病情活动指数（BASDAI）评分,分为急性期 A组（17例）和慢性期B组（13例）,另选健康志愿者C组（20例）,行骶髂关节常规 MR扫描、T2＊mapping及DWI,分别测量骶髂关节骨髓水肿区及相对正常区域的T2＊值和 ADC值,并对3组间的均值差异和A、B组与BASDAI评分关系进行统计分析。结果 A组的T2＊值和ADC值均大于B组和C组,差异有统计学意义（P〈0.05）；B组的T2＊值和ADC值与C组对比,无统计学差异（P〉0.05）；A、B组T2＊值和 ADC值与临床BASDAI评分呈正相关性（P〈0.05）。结论联合应用T2＊mapping 和DWI有助于 AS早期诊断并定量分析骶髂关节炎性活动性程度。Objective To evaluate the feasibility of T2 ＊mapping T2 ＊value combined with DWI ADC value in quantitative assessment of the activity of sacroiliitis.Methods 30 patients diagnosed with ankylosing spondylitis （AS）were divided into 2 groups as acute group （n=17）and chronic group （n=13）according to the BASDAI scores of the clinical severity of disease.And 20 healthy adults were recruited as control group.All groups were examined by MR with traditional sequence,T2 ＊mapping and DWI in the sacroiliac joint.The T2 ＊value and ADC value of the bone marrow edema region and normal region were measured.Furthermore,the imaging data and the clinical scores were statistical analysis and compared among three groups.Results T2 ＊values and ADC values in acute group of AS patients were higher than chronic group （P〈0.05）,as well as compared with healthy volunteers （P〈0.05）.There was no statistically significant difference between the chronic group of AS patients and control group （P〉0.05）.Positive correlation between ADC value and BASDAI was observed in patients group.Conclusion T2 ＊mapping combined with DWI imaging in AS is beneficial for early diagnosis and quantitative analysis of the activity of sacroiliitis.

关 键 词：强直性脊柱炎 磁共振成像 T2＊mapping 扩散加权成像 

分 类 号：R593.23[医药卫生—内科学] R445.2[医药卫生—临床医学]