Embosphere微球与平阳霉素碘化油乳剂介入治疗子宫肌瘤的有效性及安全性  

Comparative study on the efficacy and safety of interventional therapy of uterine fibroid using Embosphere and Pingyangmycin lipiodol emulsion

作　　者：温建生 路红娟 吴智群[2] 岳琨 李成业 

机构地区：[1]陕西省铜川矿务局中心医院介入中心,陕西铜川727000 [2]第四军医大学附属唐都医院介入放射科

出　　处：《实用放射学杂志》2016年第12期1933-1935,1944,共4页Journal of Practical Radiology

摘　　要：目的：观察 Embosphere微球与平阳霉素碘化油乳剂介入治疗子宫肌瘤的有效性及安全性。方法回顾性分析本院诊治的120例子宫肌瘤患者临床资料,按照不同治疗方式分为2组（各60例）,对照组给予平阳霉素碘化油乳剂介入治疗,研究组给予Embosphere微球介入治疗,对比2组临床疗效及安全性。结果研究组治疗总有效率（93.33%）显著高于对照组（75.00%）,有统计学意义（P〈0.05）；2组治疗后综合指标均较治疗前发生变化,其中研究组变化程度明显优于对照组（P〈0.05,P〈0.01）；另外,研究组不良事件总发生率（11.67%）显著低于对照组（26.67%）（P〈0.05）。结论 Embosphere微球较平阳霉素碘化油乳剂介入治疗子宫肌瘤疗效更佳,使用安全系数较高,具备临床实际应用价值。Objective To observe the curative effect and safety of interventional therapy of uterine fibroids using Embosphere and Pingyangmycin lipiodol emulsion.Methods The clinical data of 120 cases with uterine fibroids treated in our hospital were reviewed,and the patients were according to the different treatments given,divided into two groups （each with 60 cases）.Patients in control group were treated with interventional therapy of Pingyangmycin lipiodol emulsion,while patients in the study group were given interventional therapy of Embosphere.The clinical efficacy and safety in the two groups were compared.Results The total efficiency in the study group was 93.33%,which was significantly higher than that in the control group （75.00%）,and the difference was statistically significant （P〈0.05）.The comprehensive indexes after the treatment were improved in both groups compared with those before the treatment,and the improvement in the study group was significantly better than the control group （P〈0.05,P〈0.01）.Besides,the total incidence of adverse effects in the study group was 11.67%,which was significantly lower than that in the control group （26.67%）（P〈0.05）. Conclusion The interventional therapy using Embosphere has better effect on uterine fibroid compared with the therapy using Pingyangmycin lipiodol emulsion,which is worthwhile to be brought into clinical application.

关 键 词：Embosphere微球 平阳霉素碘化油乳剂 介入治疗 子宫肌瘤 

分 类 号：R815[医药卫生—放射医学] R737.33[医药卫生—临床医学]