利巴韦林联合复方白玉散治疗婴幼儿疱疹性咽炎临床疗效评价  

Clinical Efficacy Observation of Ribavirin Combined with Fufang Baiyu San in Treating Infant Herpes Pharyngitis

作　　者：刘小莉 刘玲[2] 文花 王莹[2] 葛云霞[2] 刘晓蓉[2] 

机构地区：[1]江苏省句容市妇幼保健院,江苏镇江212400 [2]南京中医药大学附属中西医结合医院,江苏南京210028

出　　处：《中国药业》2016年第24期28-30,共3页China Pharmaceuticals

基　　金：江苏省中医药局科技项目;项目编号:LZ09065

摘　　要：目的观察利巴韦林联合复方白玉散治疗婴幼儿疱疹性咽炎的临床疗效。方法将2015年4月至2016年4月治疗的疱疹性咽炎患儿110例随机分为两组,治疗组(56例),应用利巴韦林喷雾联合复方白玉散外喷治疗,对照组(54例)仅应用利巴韦林喷雾治疗。治疗后比较两组疗效、症状消失时间和平均治愈时间等。结果治疗后,治疗组总有效率为98.21%,高于对照组的88.89%,差异有统计学意义(P<0.05);治疗组平均退热时间、疱疹消失时间、流涎症状消失时间和平均治愈时间均短于对照组,差异有统计学意义(P<0.05),均较对照组缩短(P<0.01)。结论利巴韦林喷雾联合复方白玉散治疗婴幼儿疱疹性咽炎,能提高临床疗效,缩短疗程,较单一给药疗效更佳,具有推广价值。Objective To study the clinical efficacy of ribavirin combined with Fufang Baiyu San in the treatment of infant herpes pharyngitis. Methods 110 cases of infant herpes pharyngitis in the hospital from April 2015 to April 2016 were randomized into the observation group（n =56） with treatment of ribavirin combined with Fufang Baiyu San and the control group（n =54） with treatment of ribavirin spray. The clinical efficacy,symptom disappearance time and average cure time in two groups were compared. Results The total effective rate after treatment in the observation group（98.21% ） was higher than the control group（88.89% ） with statistical difference（ P 〈 0. 05）. The symptom disappearance time and average cure time were significantly decreased in the observation group than the control group with statistical difference（P 〈 0.05）. The average disappearance time of fever and herpes were obviously reduced in the observation group than the control group with statistical difference（ P 〈 0. 01）. Conclusion The treatment of ribavirin combined with Fufang Baiyu San can increase the clinical efficacy and shorten the treatment course with better efficacy than the single drug,which is worthy of clinical promotion.

关 键 词：利巴韦林 复方白玉散 婴幼儿 疱疹性咽炎 临床疗效 

分 类 号：R969.4[医药卫生—药理学] R978.7[医药卫生—药学]