西安市2013—2015年男男性行为人群HIV新发感染影响因素分析  

Incidence and influencing factors of new HIV infection among MSM in Xi'an city,2013-2015

作　　者：卫晓丽[1] 李恒新[1] 黄晓丹[1] 郑海潮[1] 周安秦 何其聪 

机构地区：[1]西安市疾病预防控制中心性病艾滋病防治科,陕西710054 [2]西安市你我健康中心 [3]陕西省红丝带志愿者协会

出　　处：《中国公共卫生》2016年第12期1609-1612,共4页Chinese Journal of Public Health

摘　　要：目的 了解陕西西安市男男性行为人群（MSM）艾滋病病毒（HIV）既往感染和新发感染状况。方法通过滚雪球和同伴推动方法于2013—2015年在西安市招募MSM,面对面一对一问卷调查和静脉采血3-5 m L,应用BED HIV-1 IgG捕获酶免疫法（BED-CEIA）结合病程判断既往感染和新发感染。结果 2 441名调查对象平均年龄（28.98±7.54）岁,未婚占70.8%（1 728/2 441）,在本市居住时间≥2年占81.5%（1 989/2 441）,大专及以上占78.1%（1 907/2 441）,认同自己为男男同性恋者占75.5%（1 844/2 441）,寻找性伴场所最多的为网络,占50.6%（1 235/2 441）。83.7%（2 042/2 441）的调查对象在近6个月内与同性发生过无保护性肛交性行为。HIV总感染率7.29%（178/2 441）,进行BED检测163例,发现新发感染71例,新发感染者占39.9%（71/178）,估算发病率为6.08%。使用助性剂是新发感染的危险因素（OR=2.082,95%CI=1.135-3.820）,最近12个月进行HIV检测是其保护因素（OR=0.234,95%CI=0.131-0.417）。结论 西安市MSM的HIV感染率仍处于较高水平,定期检测可减少HIV新发感染。Objective To investigate the status and influencing factors of previous and new human immunodeficiency virus （HIV） infection among men who have sex with men （MSM） in Xi＇an city. Methods A total of 2 444 MSM were recruited with snow-ball or respondent-driven sampling in Xi＇an city;a face-to-face questionnaire survey and 3 -5 ml venous blood collection for the determination of HIV immunoglobulin G （IgG） with HIV-1 subtypes B ,E and D （BED） capture enzyme immunoassay （BED-CEIA） were conducted among the MSM between 2013 and 2015. Logistic regression model was used to explore the risk factors for HIV infection. Results The average age of the MSM was 28.98 ± 7. 54 years. Of the MSM,70. 8% were unmarried;81.5% lived in local Xi＇an more than 2 years;78.1% had the education level of college or above;and 75.5% were self-identified as a gay. More than a half （50. 6% ） of the MSM looked for sexual partners via internet and 83.7% of the MSM reported unsafe anal homosexual behavior during previous 6 months. Totally 178 HIV seropositive cases were identified among the MSM, with an infection rate of 7.29%. For the 163 HIV seropositive cases with BED-CEIA,71 （39. 9% ） were new HIV infections, with an estimated incidence rate of 6. 08%. Multivariate logistic regression analysis showed that the abuse of isobutyl nitrite inhalation （Rush） was a risk factor （odds ratiol ORI =2. 082,95% confidence interval I95% CI] ：1. 135 -3. 820） and taking a test for HIV infection during previous one year was a protective factor （OR =0. 234,95% CI：O. 131 -0. 417） for new HIV infection. Conclu- sion HIV infection rate is still at a high level and regular test for HIV infection may reduce the incidents of new HIV in- fection among MSM in Xi＇an city.

关 键 词：MSM BED-CEIA HIV新发感染 影响因素 

分 类 号：R512.91[医药卫生—内科学]