妊娠期糖尿病患者孕中期母体体成分分析  

Maternal body composition in the second trimester in patients with gestational diabetes mellitus

作　　者：徐庆[1] 于晓明[1] 杨雪艳[1] 张新胜[1] 薛长勇 

机构地区：[1]中国人民解放军总医院营养科,北京100853

出　　处：《实用预防医学》2017年第1期30-32,共3页Practical Preventive Medicine

基　　金：科技部国家国际科技合作专项项目(No:2013DFA30910)

摘　　要：目的探讨妊娠期糖尿病(gestational diabetes mellitus,GDM)患者孕中期母体体成分特点。方法采用巢式病例对照研究方法,对象全部来自2012年5月20日-2013年12月31日期间参与多中心队列研究的人群,选取孕24~28周进行糖耐量筛查时诊断为GDM的142人为病例组,并在同一时期队列中未发生GDM的孕妇按照1:1比例,按其怀孕年龄、孕前体重和身高进行配对选取142人为对照组。采用多频生物电阻抗技术分析两组妇女在孕22~24周时的人体成分,比较两组间的体重(body weight,BW)、体质指数(body mass index,BMI)、去脂体质(free fat mass,FFM)、肌肉重(muscular mass,MM)、体脂(fat mass,FM)、体脂百分比(fat mass percentage,FMP)、总体水分(total body water,TBW)、细胞外水(extracellular water,ECW)和细胞内水(intracellular water,ICW)等指标的差异。结果孕中期GDM患者的BW、BMI、FM、FMP、TBW和ECW均显著高于对照组(P<0.05),而FFM、MM和ICW与对照组比较差异无统计学意义(P>0.05)。结论 GDM孕中期的体脂储备和细胞外水显著高于正常孕妇,而肌肉储备与正常孕妇无差异。Objective To explore the characteristics of the maternal body composition in the second trimester in patients with gestational diabetes mellitus （ GDM ）. Methods A nested case-control study was conducted in pregnant women who participated in a multicenter cohort research from May 20, 2012 to December 31, 2013. 142 pregnant women who were diagnosed with GDM by 75g oral glucose tolerance test （ OGTT） at 24-28 weeks of gestation （WG） were selected as the GDM group, meanwhile, 142 pregnant women without GDM in the research cohort served as the controls based on the match of pregnant age and pre-pregnancy body weight and body height. Multi-frequency bioelectrical impedance analysis was used to determine body composition in the subjects at 22-24 weeds of WG. The body weight （ BW ）, body mass index （ BMI ）, free fat mass （ FFM）, muscular mass （ MM ）, fat mass （ FM）, fat mass percentage （ FMP）, total body water （ TBW ）, extracellular water （ ECW ） and intracellular water （ICW） were analyzed and compared between the two groups. Results The BW, BMI, FM, FMP, TBW and ECW in the second trimester in the GDM group were all significantly higher than those of the control group （P〈0.05）, but no statistically significant difference was found in the FFM, MM and ICW between the two groups （P〉0.05）. Conclusions The body fat reserves and ECW of the GDM women in the second trimester are both significantly higher than those of the normal pregnant women, but their muscle reserves are similar to those of the normal pregnant women .

关 键 词：妊娠期糖尿病 多频生物电阻抗分析 人体成分 体脂 

分 类 号：R587.1[医药卫生—内分泌]