上海市外来散居儿童手足口病发病的危险因素研究  

Risk factors of hand,foot and mouth disease in the scattered migrant children in Shanghai City

作　　者：李恩国[1] 徐兴兴[1] 周洲[1] 潘浩[2] 

机构地区：[1]上海市闸北区疾病预防控制中心,上海200072 [2]上海市疾病预防控制中心

出　　处：《实用预防医学》2017年第1期57-60,共4页Practical Preventive Medicine

摘　　要：目的探讨上海市外来散居儿童手足口病发病的危险因素,为上海该类人群手足口病防控提供科学依据。方法选取2012年6月-2013年5月期间确诊的170例外来散居儿童手足口病病例作为病例组,340例同一社区外来散居健康儿童作为对照组,采用病例对照研方法开展发病危险因素研究。采用统一调查表进行调查,资料应用Epi Data 3.1软件建立数据库,使用SPSS19.0软件进行单因素和多因素非条件logistic回归分析,分析儿童手足口发病的危险因素。结果单因素分析显示看护人文化程度、家庭收入、1周内接触患者、曾去密集场所、咬手指、咬玩具、幼儿洗手频率、幼儿手清洁度、看护人洗手频率等是外来散居儿童发病的影响因素(P<0.05)。多因素分析显示1周内接触病例(OR=19.089,95%CI:9.904~36.794,P=0.000)和咬手指(OR=1.614,95%CI:1.037~2.514,P=0.034)为该类儿童手足口病发病的危险因素,而高家庭收入(OR=0.632,95%CI:0.440~0.908,P=0.013)和看护人洗手频率高(OR=0.691,95%CI:0.494~0.966,P=0.030)则为保护因素。结论影响上海市外来散居儿童手足口病发病的因素较多,要重点落实好儿童发病后的居家隔离,教育幼儿养成良好的手卫生习惯,做到不吮吸手指、饭前便后洗手。同时做好外来散居儿童家长或看护人的手卫生宣传也是防范该类儿童发病的一个重要手段。Objective To explore the risk factors of hand, foot and mouth disease （HFMD） among scattered migrant children in Shanghai City so as to provide scientific evidence for HFMD prevention and control. Methods One hundred and seventy scattered migrant children diagnosed with HFMD from June 2012 to May 2013 were selected as the case group, while 340 healthy scattered migrant children in the same community served as the control group. A case-control study was conducted to identify the risk factors of HFMD. Unified questionaires were used in this investigation, and EpiData 3.1 software was employed for setting up a database. SPSS19.0 software was applied to performing univariate and multivariate unconditional logistic regression analyses. Results Univariate logistic regression analysis showed that caregiver＇ s education level, family income, contacting with patients within 1 week, visit to densely populated places, finger-biting, toy-biting, young children＇ s frequency of hand washing, cleanliness of children＇ s hands, caregivers ＇ hand washing frequency were the factors influencing HFMD onset in the scattered migrant children. Mult- ivariate conditional logistic regression analysis showed that contacting with HFMD cases within 1 week （ OR = 19. 089, 95% CI：9. 904 -36.794, P=0.000） and finger-biting （ OR= 1.614, 95%CI：1.037-2.514, P=0.034） were the risk factors for HFMD in the scattered migrant children, while high family income （ OR = 0.632, 95%CI：0.440-0.908, P= 0.013 ） and high frequency of caregivers＇ hand washing （ OR=0.691, 95%CI：0.494-0.966, P=0.030） were the protective factors. Conclusions There are many factors affecting HFMD incidence in the scattered migrant children in Shanghai City. Emphasis should be placed on implementing home quarantine after HFMD onset and educating children to develop good habits of hand hygiene, including no sucking fingers and washing hands before meals and after using toilets. Publicity campaign regarding promoting hand hygiene of parents and ca

关 键 词：外来散居儿童 手足口病 危险因素 病例对照研究 

分 类 号：R512.5[医药卫生—内科学]