Design, Synthesis and Fungicidal Activity of Novel Strobilurin-l,2,4-Triazole Derivatives Containing Furan or Thiophene Rings  

作　　者：LIU Yang LIU Ming ZHANG Dongkai HUA Xuewen WANG Baolei ZHOU Sha LI Zhengming 

机构地区：[1]State Key Laboratory of Elemento-ovganic Chemistry, Collaborative Innovation Center of Chemical Science and Engineering(Tianjin), Nankai University, Tianjin 300071, P. R. China

出　　处：《Chemical Research in Chinese Universities》2016年第6期952-958,共7页高等学校化学研究（英文版）

摘　　要：A series of strobilurin-l,2,4-triazole derivatives containing a furan or thiophen ring was designed andsynthesized. The structures of the compounds were characterized by 1H NMR, 13C NMR and HRMS spectra. Thebioassays indicated that the fungicidal activities of compounds 10b（EC50=14.82 mg/L） and 10c（EC50=18.72 mg/L）against Cercospora arachidicola Hori in vitro were much higher than that of Azoxystrobin as control（EC50=40.54mg/L） and the fungicidal activities of compounds 10u（EC50=8.66 rag/L） and 10n（EC50=9.89 rag/L） against Rhizotoniacerealis in vitro were higher than that of the same control（EC50=10.86 rag/L）. Compounds 10b, 10c, 1011 and 10kcould be considered as the leading compounds for further investigation.

关 键 词：STROBILURIN FUNGICIDAL activity 1 2 4-Tfiazole Azoxystrobm 

分 类 号：O[理学]