原发性腹膜后脂肪肉瘤完整切除术后局部复发  

Local recurrence after complete resection of primary retroperitoneal liposarcoma

作　　者：张建新[1] 金炜东[1] 王再兴[1] 马丹丹[1] Zhang Jianxin Jin Weidong Wang Zaixing Ma Dandan(Department of General Surgery, Wuhan General Hospital of Guangzhou Command, Wuhan 430070, Chin)

机构地区：[1]广州军区武汉总医院普通外科,武汉430070

出　　处：《中华普通外科杂志》2016年第12期1008-1010,共3页Chinese Journal of General Surgery

摘　　要：目的探讨原发性腹膜后脂肪肉瘤的治疗经验，寻找影响其术后复发的因素。方法回顾性分析2007年1月至2012年6月期间广州军区武汉总医院收治的47例原发性腹膜后脂肪肉瘤完整的整块切除术后患者的临床资料，随访术后3年局部复发情况，以与术后局部复发有关的因素为变量组进行单因素及多因素分析。结果本组47例原发性腹膜后脂肪肉瘤患者3年复发率为62％。单因素分析及多因素分析均提示术前是否行穿刺病理检查、组织学亚型、肿瘤体积及是否外侵对原发性腹膜后脂肪肉瘤完整切除术后局部复发均有影响（均P〈0．05）。结论术前行穿刺病理检查、组织学亚型分化差、肿瘤体积大、对周围组织外侵的原发性腹膜后脂肪肉瘤患者在肿瘤完整切除术后局部复发率高。Objective To investigate factors impacting on local recurrence in cases of primary retroperitoneal liposarcoma （RPLS） after complete enbloc resection. Methods The clinical data of 47 cases of primary retroperitoneal liposarcoma were retrospectively analyzed. Results 3-year local recurrence rate was 62%. Single and multiple regression analysis showed preoperative needle biopsy, histological subtype, tumor size and capsular invasion were all risk factors related to postoperative local recurrence in primary retroperitoneal liposarcoma undergoing complete resection （P 〈 0. 05 ） . Conclusion Preoperative aspiration biopsy, tumor poor differentiation, large tumor size tumor extracapsular spread all lead to high local recurrence rate after complete resection of primary retroperitoneal liposarcoma.

关 键 词：脂肪肉瘤 肿瘤复发 局部 回归分析 

分 类 号：R735.4[医药卫生—肿瘤]