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作 者:李婷[1] 刘二勇[2] 张佩如[1] 肖月[1] 李运葵[1] 夏勇[1] 吴建林[1] 成诗明[2] 周林[2] 何金戈[1]
机构地区:[1]四川省疾病预防控制中心结核病防治所,成都610041 [2]中国疾病预防控制中心结核病预防控制中心
出 处:《结核病与肺部健康杂志》2016年第3期209-216,共8页Journal of Tuberculosis and Lung Health
摘 要:目的分析四川省报告发现的涂阴与涂阳肺结核流行特征,为提出有针对性的防控策略提供科学依据。方法利用2005-2014年“传染病报告信息管理系统”统计分析四川省涂阳、涂阴肺结核的构成及年龄、性别、地区分布等特征。结果2005-2014年,肺结核报告发病率从112.00/10万(91711例)下降到69.68/10万(56489例),下降了37.79%,年均递降率为5.14%;其中,涂阳肺结核报告发病率从47.91/10万(39228例)下降到19.91/10万(16142例),下降了58.44%,年均递降率为9.30%;涂阴肺结核报告发病率从29.99/10万(24553例)上升到42.49/10万(34444例),上升了41.68%,年均递增率为3.95%;涂阴与涂阳肺结核报告发病数的比值从2005年的0.63(24553/39228)上升到2014年的2.13(34444/16142)。2005--2014年全省涂阳肺结核中的男女患者比例(2.57:1,207309/80566)高于涂阴肺结核中的男女患者比例(2.25:1,204162/90762)(χ^2=545.67,P〈O.05)。15岁以下人群涂阴与涂阳肺结核报告发病例数的比值从2005年的1.74(766/439)上升至2014年的4.17(350/84)。对2005-2014年川中、川南、川东北、川西地区涂阴患者在活动性肺结核中的构成比分析,川中地区涂阴构成比最高(46.93%,96010/204592),川西地区最低(34.75%,32734/94186),差异有统计学意义(χ^2=1332.73,P〈0.05)。结论四川省涂阴肺结核报告发病率逐渐上升,尤其在15岁以下人群及川中地区较为突出。Objective To analyse epidemic characteristics of smear negative and positive pulmonary tubercu- losis (TB) in Sichuan, providing scientific evidence for TB prevention and control strategy. Methods Data of composition, age, gender, region distribution of smear negative and positive TB in Sichuan were analysed using net- work reporting system of infectious diseases between 2005 and 2014. Results During the period of 2005-2014, incidence of reported TB declined by 37. 79% from 112. 00/100 000 (91 711 cases) to 69.68/100 000 (56 489 cases), the annual reduction rate was 5.14% ; incidence of reported smear positive TB decreased by 58. 44% from 47. 91/100 000 (39 228 cases) to 19.91/100 000 (16 142 cases) with the annual reduction rate of 9.30%, while incidence of smear negative TB increased by 41. 680/00 from 29.99/100 000 (24 553 cases) to 42.49/100 000 (34 444 cases) with the an- nual increasing rate of 3.95%. The ratio of reported smear negative TB to smear positive TB rose from 0. 63 (24 553/39 228) in 2005 to 2.13 (34 444/16 142) in 2014. Between 2005 and 2014, proportion of male to female in smear positive TB patients (2.57 : 1, 207 309/80 566) was higher than that in smear negative TB (2.25:1, 204 162/90 762) (χ^2 = 545.67, P〈0. 05) ; as to patients with the age of 〈15 years, the ratio of reported smear negative TB to smear posi- tive TB rose from 1.74 (766/439) in 2005 to 4. 17 (350/84) in 2014. The ratio of smear negative TB to active TB in the middle of Sichuan was the highest (46.93%, 96 010/204 592), and was significantly higher than that in west of Sichuan (34.75%,32 734/94 186, the lowest) (χ^2=1332. 731, P〈0.05). Conclusion The incidence of smear no^ntivo TB in Sichuan is raising, especially in population of 〈15 years old and in the middle of Sichuan.
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