血清降钙素原和淀粉样蛋白A在老年细菌性肺炎患者中的诊断价值  

Diagnostic value of serum procalcitonin and serum amyloid A in the diagnosis of elderly patients with bacterial pneumonia

作　　者：汪锋平[1] 王利民[2] 刘俊[1] WANG Feng- ping WANG Li -min LIU Jun(Clinical Laboratory, Quzhou People＇ s Hospital, Quzhou, Zhejiang 324000, Chin)

机构地区：[1]衢州市人民医院检验科,浙江衢州324000 [2]金华市中心医院检验科,浙江金华321000

出　　处：《中国卫生检验杂志》2016年第23期3407-3409,共3页Chinese Journal of Health Laboratory Technology

摘　　要：目的探讨PCT和SAA在老年细菌性肺炎中的应用价值。方法选取2016年4月-7月本院治疗的肺炎患者,分为细菌性肺炎组96例和病毒性肺炎组89例,另选取健康体检者100例为对照组,测定3组患者的PCT和SAA水平,对细菌性肺炎组治疗前后PCT和SAA水平进行比较,分析两者在老年细菌性肺炎中的诊断效率。结果细菌性肺炎组PCT和SAA水平明显高于病毒性肺炎组和对照组,治疗后PCT和SAA均显著降低,差异均有统计学意义(P<0.05)。细菌性肺炎组PCT和SAA的阳性率高于病毒感染组和对照组,差异均有统计学意义(P<0.05);PCT诊断细菌性肺炎的特异度、阳性预测值、阴性预测值均高于SAA,两者水平呈正相关(r=0.794,P<0.01)。结论检测PCT和SAA对老年细菌性肺炎的早期诊断和指导用药具有指导意义,诊断效率PCT优于SAA。Objective To investigate the clinical value of PCT and SAA in elderly patients with bacterial pneumonia.Methods Patients with pulmonary infection were selected from April to July,2016 in our hospital,including bacterial pneumonia group with 96 cases and viral pneumonia group with 89 cases,at the same time,100 healthy elderly patients were selected as the control group; the levels of PCT and SAA in three groups were measured; the levels of SAA and PCT in patients with bacterial pneumonia were compared before and after treatment,at the same time,the diagnostic efficiency of PCT and SAA in the elderly patients with bacterial pneumonia was analyzed. Results The levels of PCT and SAA were significantly higher in the bacterial pneumonia group than that in the viral pneumonia group and the normal control group; both PCT and SAA significantly decreased,with the differences statistically significant（ P 〈 0. 05）; the positive rates of PCT and SAA in the bacterial pneumonia group were significantly higher than the virus infection group and the normal control group,with the differences statistically significant（ P 〈 0. 05）; the specificity,positive predictive value and negative predictive value of PCT in the diagnosis of bacterial pneumonia were all higher than SAA,and both of them were positively correlated（ r = 0. 794,P 〈 0. 01）. Conclusion Detection of PCT and SAA levels in the early diagnosis of bacterial pneumonia and guide the use of drugs has a guiding significance,and the efficiency of PCT in the diagnosis of bacterial pneumonia is better than that of SAA.

关 键 词：降钙素原 淀粉样蛋白A 老年患者 细菌性肺炎 

分 类 号：R446.1[医药卫生—诊断学]