钠钾镁钙葡萄糖注射液在腹腔镜下子宫全切术中输注对患者血糖、电解质和酸碱平衡的影响  

Influence of sodium potassium magnesium calcium and glucose injection on intraoerative blood glucose, electrolytes, and acid-base

作　　者：周松芳[1] 李晓佩[1] 王丽娟[2] 魏晓永[2] 姜丽华[2] 

机构地区：[1]河南省郏县妇幼保健院,467100 [2]郑州大学第三附属医院

出　　处：《中国实用医刊》2016年第23期71-73,共3页Chinese Journal of Practical Medicine

摘　　要：目的以乳酸林格氏注射液为对照，评价钠钾镁钙葡萄糖注射液（SPMCG）在腹腔镜下子宫全切术术中输注对患者血糖、电解质和酸碱平衡的影响。 方法选择全身麻醉下择期行腹腔镜下子宫全切术患者50例，ASA分级Ⅰ或Ⅱ级，采用随机数字表法分为实验组和对照组，每组25例。实验组术中输注SPMCG，对照组术中输注乳酸钠林格氏液，分别在入室后以10 ml/（kg·h）的速度输注500 ml后行麻醉诱导，诱导后以10 ml/（kg·h）的速度维持至手术结束。于输液前（T0）、输液量为10 ml/kg（T1）、输液量为20 ml/kg（T2）和输液量为30 ml/kg（T3）时检测患者的动脉血气分析和血糖，并记录。 结果输液后实验组血糖水平、pH值和乳酸水平在各时间点均无明显变化；对照组血乳酸水平在T2和T3时间点时明显升高（P〈0.05），pH值在T2和T3时间点时明显降低（P〈0.05），血糖水平在各时间点无明显变化；两组电解质水平均无明显变化。 结论钠钾镁钙葡萄糖注射液与复方乳酸钠注射液在腹腔镜手术术中输注比较，其可避免乳酸水平的升高以及维持酸碱平衡的稳定，对血糖水平和电解质水平的影响效果相当。Objective To compare the effects of sodium potassium magnesium calcium and glu- cose injection and lactate Ringer＇s injection injected on intraoperative bloodglucose, electrolytes, and acid- base balance in laparoscopic surgery. Methods Forty patients scheduled for laparoscopic total hysterec- tomy were randomly divided into the experiment group （group E, n = 25 ）and the control group（ group C, n =25）. Group E was infused with sodium potassium magnesium calcium and glucose injection, while group C was infused with sodium lactate Ringer＇s injection at the rate of 10 ml/（ kg·h）. Arteria blood glucose,lactate, electrolytes, and pH were measured before infusion （T0）, at the time of the infusion vol- ume reaching 10 ml/kg（T1）, 20 ml/kg（T2） ,and 30 ml/kg（T3）. Results No significant change in arteria blood glucose, lactate, electrolytes, and pH in group E at T1,3＂2 and 3＇3 after sodium potassium magnesium calcium and glucose injection injected. In group C, the level of blood lactate was increased, the level of pH was decreased at T2 and T3 （P 〈 0. 05 ） , and no significant change in arteria blood glu- cose. No significant changes in electrolytes were found in both groups. Conclusions Sodium potassium magnesium calcium and glucose injection has the equivalent effects on maintenance of electrolytes and arteria blood glucose as sodium lactate Ringer＇ s injection. It can aviod the hyperlactacidemia caused by large volume of lactate Ringer＇s injection and maintain the acid-base balance.

关 键 词：钠钾镁钙葡萄糖注射液 腹腔镜手术 子宫全切术 血糖 水电解质平衡 酸碱平衡 

分 类 号：R614[医药卫生—麻醉学]