单独病灶清除植骨融合与联合后路椎弓根螺钉内固定术治疗胸腰椎布鲁杆菌性脊柱炎疗效比较  被引量:5

Comparison of clinical effect of bone grafting fusion debridement alone,and combined with posterior pedicle screw fixation in the treatment of thoracolumbar Brucella spondylitis

在线阅读下载全文

作  者:侯文根[1] 路坦[1] 张超[1] 孙晓辉[1] HOU Wen-gen LU Tan ZHANG Chao SUN Xiao-hui(Department of the Second Osteology, the First Affiliated Hospital of Xinxiang Medical University, Weihui 453100, Henan Province, China)

机构地区:[1]新乡医学院第一附属医院骨二科,河南卫辉453100

出  处:《新乡医学院学报》2016年第1期48-50,共3页Journal of Xinxiang Medical University

基  金:河南省医学科技攻关计划项目资助(编号:201304029)

摘  要:目的比较单独病灶清除植骨融合与联合后路椎弓根螺钉内固定术治疗胸腰椎布鲁杆菌性脊柱炎的效果。方法选择2012年4月至2014年4月在新乡医学院第一附属医院接受手术治疗的胸腰椎布鲁杆菌性脊柱炎患者78例,随机分为观察组和对照组,每组39例。观察组患者实施病灶清除、植骨融合及后路椎弓根螺钉内固定术,对照组患者单独予以病灶清除、植骨融合手术。随访6个月,比较2组患者的治疗效果、治疗前后神经功能Frankel分级及影像学评分,分析患者神经功能Frankel分级与影像学评分的相关性。结果观察组患者治疗总有效率(89.74%)显著高于对照组(71.79%)(P<0.05)。治疗后观察组患者神经功能Frankel分级显著优于对照组(P<0.05)。治疗后2组患者影像学评分均有改善,但观察组患者1、3、6个月的影像学评分均显著高于对照组(P<0.05)。布鲁杆菌性脊柱炎患者的神经功能Frankel分级水平与影像学评分呈正相关(P<0.01)。结论病灶清除植骨融合联合后路椎弓根螺钉内固定手术方案治疗布鲁杆菌性脊柱炎的疗效更佳,患者神经功能恢复更好。Objective To observe and compare the clinical effect of bone grafting fusion debridement alone, and com- bined with posterior pediele screw fixation in the treatment of thoracolumbar Brucella spondylitis. Methods A total of 78 cases of patients with thoracolumbar Brucella spondylitis who accepted operation treatment in the First Affiliated Hospital of Xinxiang Medical University from April 2012 to April 2014 were selected ,and were randomly divided into observation group and control group with 39 cases in each group. The patients in observation group accepted debridement,interbody fusion and pedicle screw internal fixation through posterior approach operation treatment,while the patients in control group accepted debridement, bone graft fusion operation scheme only. After 6 months of follow-up, the clinical efficacy, nerve function Frankel grading and the imaging scores of the two groups before and after treatment were compared, and the correlation between Frankel classification and image score was analyzed. Results The total effective rate of observation group( 89.74% ) was significantly higher than that of control group (71.79% ) ( P 〈 0. 05 ). After treatment, the Frankel classification of observation group was better than that of control group ( P 〈 0.05 ). The radiographic score of the two groups after treatment improved than before treatment, which in observation group was significantly higher than that in control group at 1,3 and 6 months of treatment( P 〈 0.05 ). Frankel classification had positive correlation relationship with the radiographic score ( P 〈 0.01 ). Conclusion Debridement and bone graft fusion, and pediele screw internal fixation via posterior operation scheme for the treatment of patients with Brucella spondylitis had better curative effect and neurological function recovery.

关 键 词:病灶清除植骨融合 后路椎弓根螺钉内固定术 胸椎 腰椎 布鲁杆菌性脊柱炎 

分 类 号:R681.5[医药卫生—骨科学]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象