联合米非司酮及利凡诺对疤痕子宫中期妊娠引产的疗效观察  

Observation curative effect by mifepristone combined with rivanol for induced labor in scarred uterus midtrimester pregnancy

作　　者：陈艳[1] 言齐 黄敏嫦 

机构地区：[1]广东省佛山市南海区第七人民医院妇产科,528247

出　　处：《中国实用医药》2016年第31期38-39,共2页China Practical Medicine

摘　　要：目的观察联合米非司酮及乳酸依沙吖啶注射液(利凡诺)对疤痕子宫患者中期妊娠引产的疗效。方法 80例疤痕子宫中期引产的患者,随机分为对照组及实验组,各40例。对照组采用利凡诺引产,实验组在对照组基础上联合米非司酮引产,比较两组引产总时间、宫缩发动时间、宫缩至流产结束时间及流产后有效率及出血量。结果对照组的宫缩至流产结束时间与实验组比较差异无统计学意义(P>0.05);实验组引产总时间和宫缩发动时间少于对照组(P<0.05)。实验组有效率为100.0%,高于对照组的87.5%(P<0.05)。实验组流产后出血量为(71.49±31.45)ml,少于对照组的(99.38±33.79)ml,差异有统计学意义(P<0.01)。结论米非司酮联合利凡诺引产对于疤痕子宫中期妊娠引产患者的疗效可靠,方法简便易行、出血量少、有效率及安全性高,并有利于缩短引产时间及产程进展。Objective To observe curative effect by mifepristone combined with ethacridine lactate injection （rivanol） for induced labor in scarred uterus midtrimester pregnancy. Methods A total of 80 patients receiving induced labor in scarred uterus midtrimester pregnancy were randomly divided into control group and experimental group, with 40 cases in each group. The control group received rivanol for induced labor, and the experimental group received additional mifepristone for induced labor. Comparison was made on total time of induced labor, uterine contraction start time, duration between uterine contraction and abortion, effective rate and bleeding volume after abortion between the two groups. Results There was no statistically significant difference of duration between uterine contraction and abortion between the control group and the experimental group （P〉0.05）. The experimental group had shorter total time of induced labor and uterine contraction start time than the control group （P〈0.05）. The experimental group had higher effective rate as 100.0% than 87.5% in the control group （P〈0.05）. The experimental group had fewer bleeding volume after abortion as （71.49±31.45） ml than （99.38±33.79） ml of the control group, and the difference had statistical significance （P〈0.01）. Conclusion Combination of mifepristone and rivanol shows creditable effect for induced labor in scarred uterus midtrimester pregnancy. This method is easily operated, along with few bleeding volume and high effective rate and safety. It is beneficial for shortening induced labor time and progress.

关 键 词：米非司酮 乳酸依沙吖啶注射液 疤痕子宫 中期妊娠 

分 类 号：R719.3[医药卫生—妇产科学]