强化血糖控制对重症急性胰腺炎患者血糖变异性的影响  

Effect of Intensive Glucose Control on Blood Glucose Variability in Patients With Severe Acute Pancreatitis

作　　者：吴行廷 

机构地区：[1]福建省南平市第二医院消化内科,福建南平354200

出　　处：《中国卫生标准管理》2016年第23期55-56,共2页China Health Standard Management

摘　　要：目的 探讨强化血糖控制对重症急性胰腺炎患者血糖变异性的影响。方法 选取我院2006年8月~2016年8月收治的56例重症急性胰腺炎患者为研究对象,将所有患者根据血糖控制分为对照组和研究组,每组28例,对照组患者血糖控制在10.1~12.0 mmol/L,研究组患者血糖控制在4.4~6.1 mmol/L,对比两组患者治疗后空腹血糖（FBG）、C反应蛋白（CRP）水平以及APACHEⅡ评分变化,住院时间及呼吸机使用时间。结果 治疗3 d后研究组患者的FBG、CRP水平以及APACHEⅡ评分低于对照组,两组比较差异有统计学意义（P〈0.05）,且研究组患者的住院时间及呼吸机使用时间少与对照组,两组比较差异有统计学意义（P〈0.05）。结论 强化血糖控制能有效减少重症急性胰腺炎患者住院时间及呼吸机使用时间,降低血糖变异性,具有临床应用价值。Objective To explore improved glycemic control of blood glucose variability in patients with severe acute pancreatitis. Methods 56 cases of patients with glycemic control were seclected from Augost 2006 to August 2016, were divided into the study group and the control group, 28 patients in each group, the control group of patients were control blood glucose in 10.1 to 12.0 retool/L, and patients in the control group were control blood glucose in 4.4 to 6.1 retool/L, the changes of fasting blood glucose （ FBG ）, C reactive protein （ CRP ） and APACHE II score, the length of hospital stay and the time of using ventilator were compared between the two groups. Results After 3 d treatment of patients in the study group, FBG, CRP level and APACHE score lower than the control group, there was significant difference between two groups （P 〈 0.05 ）, and the patients in the study group, hospitalization time and ventilation time and the control group, there was significant difference between two groups （P 〈 0.05 ） . Conclusion Intensive glucose control can effectively reduce the hospitalization time of patients with severe acute pancreatitis and the time of ventilator use, reduce blood glucose variability, and has clinical application value.

关 键 词：强化血糖控制 重症急性胰腺炎 血糖变异性 

分 类 号：R657.5[医药卫生—外科学]