参芪复方治疗糖尿病及其并发症的动物实验研究  

Experimental Animal Study on ShenQi Compound Recipe in Treating Diabetes and Its Complications

作　　者：刘雪辉[1,2] 富晓旭[1] 谢春光[2] 

机构地区：[1]成都中医药大学临床医学院,四川成都610075 [2]成都中医药大学附属医院

出　　处：《西部中医药》2016年第11期135-139,共5页Western Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金资助项目(编号81273749)

摘　　要：从改善糖尿病脂代谢紊乱以及治疗糖尿病大血管病变、糖尿病肾病、糖尿病心肌病、糖尿病骨骼肌病变及其机制6方面入手对参芪复方治疗糖尿病及其慢性并发症的动物实验研究进行综述,指出大量动物实验研究已证明参芪复方除了具有降糖、降脂作用外,在防治糖尿病相关并发症包括糖尿病大血管病变、糖尿病肾病、糖尿病心肌病、糖尿病骨骼肌等方面具有多重作用,其机制不仅限于血糖、血脂的下降,减轻糖脂毒性,也包括抑制氧化应激、抑制细胞凋亡、抗炎、抗纤维化等多重作用。The experimental animal study of diabetes and its complications from pathogenesis were summarized from the aspects of diabetes dyslipidemia improvement, macroangiopathy of diabetes, diabetic nephropathy, diabetic cardiomyopathy, diabetic skeletal diseases, It was point out that ShenQi compound recipe can not only reduce glucose, lipid, but also prevent and treat relative complications, including macroangiopathy of diabetes, diabetic nephropathy, diabetic cardiomyopathy, diabetic skeletal diseases, its mechanism is to reduce toxicity of glycolipid by reducing glucose and lipid, also to suppress oxidative stress, cell apoptosis, resist inflammation and fibrosis.

关 键 词：糖尿病 参芪复方 动物实验 综述 

分 类 号：R963[医药卫生—微生物与生化药学]