孕妇产前凝血功能检测的临床意义  

Clinical significance of prenatal coagulation testing in pregnant women

作　　者：吴长蓉[1] 唐熟能[1] 

机构地区：[1]厦门大学附属第一医院检验科,福建厦门361003

出　　处：《中国现代医生》2016年第31期111-113,共3页China Modern Doctor

摘　　要：目的 研究孕妇产前凝血功能检测的临床意义,并对其结果进行分析。方法 选取2014年8月-2016年5月期间在我院进行产前检查的73例妊娠高血压综合征（简称妊高征）孕妇作为研究对象,其中41例孕妇为轻度妊高征,32例孕妇为中、重度妊高征;并选取同期在我院进行产前检查的47例健康妊娠孕妇作为对照。所有孕妇均采用Rayto RAC-1800全自动血凝分析仪对其凝血功能指标PT、TT、APTT及FIB进行检测,并对检测结果进行分析。结果 轻度妊高征孕妇和中、重度妊高征孕妇的PT、TT及APTT时间均明显较健康妊娠孕妇短,差异有统计学意义（P〈0.05）,且轻度妊高征孕妇与中、重度妊高征孕妇的FIB水平显著高于健康妊娠孕妇,差异有统计学意义（P〈0.05）;与轻度妊高征孕妇比较,中、重度妊高征孕妇的PT、TT及APTT时间较短,FIB水平较高,差异有统计学意义（P〈0.05）。结论 对妊娠期孕妇的凝血状态进行检测可有效预防多种并发症的发生,并有利于降低妊高征的发生率,从而减少妊娠不良结局的发生,为生产中的母婴安全提供可靠保障,在临床中具有较大价值。Objective To study the clinical significance of prenatal coagulation testing in pregnant women, and to ana- lyze the results. Methods A total of 73 pregnant women with pregnancy-induced hypertension （PIH） who were given prenatal examinations in our hospital from August 2014 to May 2016 were selected as the research subjects. Among them, 41 cases were mild PIH, and 32 cases were moderate to severe PIH; 47 cases of healthy pregnant women who were given prenatal examination in the same period were selected as research subjects. PT, TT, APTT and FIB were measured by Rayto RAC-1800 automatic hemagglutination analyzer in all pregnant women, and the results were ana- lyzed. Results PT, TT and APTT time of pregnant women with mild PIH, moderate PIH and severe PIH was significantly shorter than that in the healthy pregnant women（P〈0.05）, and the differences were statistically significant（P〈0.05）. The levels of FIB in pregnant women with mild PIH and those with moderate or severe PIH were significantly higher than those in healthy pregnant women, and the differences were statistically significant（P〈0.05）; The PT, TT and APTT time of pregnant women with moderate to severe PIH were shorter and the level of FIB was higher, which was significantly dif- ferent from those in the pregnant women with mild PIH, the differences were statistically significant （P〈0.05）. Conclu- sion The detection of coagulation status in pregnant women can effectively prevent the occurrence of many complica- tions and is beneficial to reducing the incidence of PIH, thus reducing the occurrence of adverse pregnancy outcomes and providing reliable protection for mother-to-child safety during labor, which is of great clinical value.

关 键 词：孕妇 凝血功能 凝血酶 纤维蛋白原 

分 类 号：R714.1[医药卫生—妇产科学]