运动对炎症反应的抑制作用  

Anti-inflammatory action of exercise training

作　　者：安祥博 张幼怡[1] 宋峣[1] 

机构地区：[1]北京大学第三医院血管医学研究所卫生部心血管分子生物学与调节肽重点实验室心血管受体研究北京市重点实验室,100191

出　　处：《中国心血管杂志》2016年第6期432-437,共6页Chinese Journal of Cardiovascular Medicine

基　　金：国家自然科学基金重点项目(81530009)~~

摘　　要：炎症反应是一把双刃剑,它既是机体最重要的防御机制之一,同时也会对组织器官造成损伤。越来越多的证据表明炎症是促使多种疾病发生发展的重要因素,也是动脉粥样硬化、慢性心力衰竭、阿尔茨海默病和2型糖尿病等疾病的主要病理过程。近年来对这些疾病的抗炎治疗已成为研究热点,而运动作为一种安全易行的方法,其抗炎作用也越来越受到关注。本文将就运动训练在动脉粥样硬化、阿尔茨海默病及纤维化等病理改变中对炎症反应的抑制作用及相关机制进行讨论。Inflammatory reaction , like a double-edged sword , is one of the most important defense mechanisms of the organism ,but in the meanwhile it leads to tissue and organ injury .Growing evidence has indicated that inflammation not only plays a key role in the onset and progression of many diseases ,but is the basic pathological process in atherosclerosis ,chronic heart failure,Alzheimer disease and type 2 diabetes, etc.In recent years anti-inflammatory therapy on these diseases has been a research hotpot ,and exercise,as a safe and easy-to-accomplished way ,has been paid more and more attention on its anti-inflammatory action.In this review we will discuss the inhibitory effect of exercise training on inflammation in atherosclerosis , Alzheimer disease and fibrosis and underlying mechanisms .

关 键 词：炎症 运动疗法 

分 类 号：R87[医药卫生—运动医学]