右美托咪啶静脉泵注治疗麻醉诱导后阴茎勃起的临床研究  

Clinical study of penile erection after anesthesia induction of dexmedetomidine intravenous infusion therapy

作　　者：蔡璐[1] 刘冬炎[1] 陶水祥[2] CAI Lu LIU Dongyan TAO Shuixiang(Anaesthesia Department, The Second Hospital of Shaoxing, Shaoxing 312000, Zhejiang, China Urology Department, Shaoxing People＇ s Hospital, Shaoxing 312000, Zhejiang, China)

机构地区：[1]绍兴第二医院麻醉科,浙江绍兴312000 [2]绍兴市人民医院泌尿外科,浙江绍兴312000

出　　处：《中国性科学》2016年第12期25-28,共4页Chinese Journal of Human Sexuality

基　　金：浙江省医学会临床科研基金项目(2011ZYC-A01)

摘　　要：目的:研究右美托咪啶静脉泵注射对麻醉诱导后阴茎异常勃起的治疗效果,以期为临床手术提供一定的参考。方法:选取2013年1月至2015年3月间入院间行择期手术,在全身麻醉后留置导尿管发生阴茎异常勃起的患者47例。应用序贯法将患者随机分为A组(15例)、B组(16例)与C组(16例)。其中A组不采取特殊处理,B组静脉泵注射右美托咪啶0.5μg/(kg·h)至阴茎疲软,C组静脉泵注射右美托咪啶1.0μg/(kg·h)至阴茎疲软。观察三组阴茎疲软时间、治疗前后血压与心率的变化,同时观察三组患者麻醉情况。结果:A组平均勃起时间为(19.0±10.2)min,B组为(15.3±5.8)min,C组为(4.9±1.4)min。C组勃起时间显著短于A组与B组(P<0.05),A组与B组勃起时间并无显著差异(P>0.05)。治疗前三组患者的血压与心率均无显著差异(P>0.05);治疗后即刻A组血压心率并无显著变化,但B组与C组血压显著升高、心率则不同程度下降,以C组改善显著(P<0.05);治疗30min后,三组患者血压与心率均降低到治疗前水平。C组平均麻醉苏醒时间长于B组与A组,且B组长于A组,但三组并无显著差异(P>0.05);同时三组患者术后恶心、呕吐与意识障碍病例比例并无显著差异(P>0.05)。结论:综上所述,全身麻醉诱导后阴茎异常勃起的患者应用较大剂量的右美托咪啶治疗可快速改善阴茎异常勃起的情况,并且对麻醉的影响较小,但应注意观察患者心率与血压的变化。Objectives： To study the therapeutic effect of anesthesia induced penile erection of dexmedetomidine intravenous infusion therapy in order to provide a reference for clinical surgery. Methods： 47 patients with anesthesia induced penile erection from January 2013 to March 2015 were selected. By sequential method,they were randomly divided into group A（ 15 cases）,group B（ 16 patients） and group C（ 16）. Group A did not receive special treatment,group B received 0. 5μg /（ kg·h） dexmedetomidine intravenous injection to weak penis and Group C received 1. 0μg /（ kg·h） right dexmedetomidine intravenous injection to weak penis. Penis weakness time changes in blood pressure and heart rate before and after treatment of three groups were observed,while anesthesia condition of three groups was observed. Results： Average erectile time of group A was（ 19. 0 ± 10. 2） min,in group B it was（ 15. 3 ± 5. 8） min and in group C it was（ 4. 9 ± 1. 4） min. Erection time of group C was significantly shorter than that of group A and group B（ P〈0. 05）,without significant difference between group A and group B in the aspect of erection time（ P〉0. 05）. Blood pressure and heart rate of three groups before treatment had no significant difference（ P〉0. 05）; after treatment immediately,there was no significant change in blood pressure and heart rate in group A,but blood pressure significantly increased in group B and group C,heart rate decreased to varying degrees. Group C improved significantly（ P〈0. 05）; 30 min after treatment,blood pressure and heart rate of three groups decreased to pre- treatment levels. Average anesthesia recovery time of Group C was longer than these in group B and group A,the recovery time of group B was longer than that in group A,but there was no significantly difference among three groups（ P〉0. 05）; while postoperative nausea,vomiting and unconsciousness of three groups had no significant difference（ P〉0. 05）. Conclusion： In summary,afte

关 键 词：右美托咪啶 静脉泵注射 麻醉 阴茎勃起 

分 类 号：R697.14[医药卫生—泌尿科学]