屈螺酮炔雌醇对人工流产术后患者子宫内膜的修复作用研究  

Effect study of oral Yasmin on endometrium recovery after abortion

作　　者：孙俊杰[1] 刘小利[1] SUN Junjie LIU Xiaoli.(Department of Family Planning, Chongqing Maternal and Children Health Care Hospital, Chongqing 400013, China)

机构地区：[1]重庆市妇幼保健院计划生育科,重庆400013

出　　处：《中国性科学》2016年第12期124-126,共3页Chinese Journal of Human Sexuality

摘　　要：目的:研究妇产科人流术患者在口服优思明后对子宫内膜的修复作用。方法:选择2013年8月至2015年9月在我院妇产科自愿要求终止妊娠的人工流产手术妇女148例,以数字法随机分为观察组和对照组各74例。其中观察组术后就开始服用优思明,对照组不使用优思明治疗。对比两组各时间点子宫内膜厚度、阴道出血情况、月经复潮情况以及术后并发症等。结果:两组术前以及术后1周两组子宫内膜厚度对比无差异(P>0.05),在术后2周、3周观察组子宫内膜厚度显著大于对照组(P>0.05);观察组阴道持续出血时间以及阴道流血量均显著低于对照组(P>0.05);观察组月经复潮时间显著低于对照组,并且观察组首次月经复潮月经量似正常月经量患者比例显著高于对照组,而少于月经量、多于月经量患者比例均显著低于对照组(P>0.05);观察组出现并发症比例为2.70%(2/74),显著低于对照组的18.92%(14/74)(P>0.05)。结论:在实施人流术后口服优思明不仅能有效促进子宫内膜的修复效果,而且显著降低阴道出血量、改善月经复潮情况。Objectives： To explore the effect of oral Yasmin on endometrium recovery after abortion.Methods： 148 women received artificial abortion in our hospital from August 2013 to September 2015 were randomly divided into observation group and control group,with 74 cases in each group. The observation group received Yasmin treatment after the operation and control group did not. The endometrial thickness,vaginal bleeding,menstruation and postoperative complications at each time point of two groups were compared. Results： Endometrial thickness prenatal and 1 week after the operation of two groups had no difference. 2 weeks,3 weeks after the operation,the endometrial thickness of observation group was significantly greater than that of control group. The vaginal bleeding time and vaginal bleeding amount of observation group were significantly lower than these of control group. The menses time of observation group was significantly lower than that of control group. The patient proportion of first menstrual volume like menstrual quantity in observation group was significantly higher than that of control group andthe proportion of patients with less amount of menstrual and more amount of menstruation in observation group was significantly lower than these of control group. Complication occurrence rate of observation group was 2. 70（ 2 /74）,which was significantly lower than that in control group of 18. 92（ 14 /74）. The differences were statistically significant（ P〈0. 05）. Conclusion： After the implementation of abortion surgery,oral Yasmin can effectively promote endometrial repair effect,reduce the amount of vaginal bleeding and improve the situation of menstruation.

关 键 词：优思明 人流手术 子宫内膜 阴道出血 月经复潮 

分 类 号：R719.34[医药卫生—妇产科学]