丹参饮合瓜蒌薤白半夏汤加减治疗食管源性胸痛临床观察  

Clinical observation of Danshen deocotion combined with Gualou-xiebai-banxia decoction on esophageal chest pain

作　　者：陈士新 翟兴红[2] 

机构地区：[1]北京市朝阳区平房社区卫生服务中心中医科,北京100123 [2]首都医科大学附属北京中医医院脾胃病科,北京100010

出　　处：《河北中医》2016年第10期1520-1523,共4页Hebei Journal of Traditional Chinese Medicine

摘　　要：目的观察丹参饮合瓜蒌薤白半夏汤加减治疗食管源性胸痛的临床疗效。方法将98例食管源性胸痛患者随机分为2组,治疗组50例予丹参饮合瓜蒌薤白半夏汤加减治疗,对照组48例予奥美拉唑肠溶片治疗。2组均治疗4周,观察2组治疗前后中医证候积分变化,比较2组疗效、中医证候疗效。结果2组治疗后中医证候积分均较本组治疗前降低(P<0.05);治疗后治疗组中医证候胸痛、泛酸、烧心积分均低于对照组(P<0.05)。总有效率治疗组94.00%,对照组81.25%,2组总有效率比较差异有统计学意义(P<0.05),治疗组临床疗效优于对照组。中医证候总有效率治疗组96.00%,对照组89.58%,2组总有效率比较差异有统计学意义(P<0.05),治疗组中医证候疗效优于对照组。结论丹参饮合瓜蒌薤白半夏汤治疗食管源性胸痛有较好疗效。Objective To observe the clinical effects of Danshen deocotion combined with Gualou-xiebai-banxia decoction on esophageal chest pain. Methods 98 patients with esophageal chest pain were randomly divided into two groups. 50 cases in treatment group were treated by modified Danshen deocotion combined with Gualou-xiebai-banxia decoction,and 48 cases in control group were treated by omeprazole enteric-coated tablets. The treatment course was 4 weeks in two groups. The traditional Chinese medicine（TCM） symptom score before and after treatment were observed in two groups. The curative effects and TCM symptom effects were compared between two groups. Results The TCM symptom score after treatment were decreased in two group（P〈0.05）. The TCM symptom scores of chest pain,pantothenic acid and heart burnt after treatment in treatment group were lower than those in control group（P〈0.05）. The total effective rate in treatment and control group was 94. 00% and 81. 25%respectively,with statistical differences（P〈0.05）. The curative effect in treatment group was superior to that in control group. The total TCM symptom effective rate in treatment and control group was 96. 00% and 89. 58% respectively,with statistical differences（P〈0.05）. The total TCM symptom effects in treatment group was superior to that in control group. Conclusion Danshen deocotion combined with Gualou-xiebai-banxia decoction has better therapeutic effect on esophageal chest pain.

关 键 词：食管疾病 并发症 胸痛 中药疗法 丹参饮 瓜蒌薤白半夏汤 

分 类 号：R975.6[医药卫生—药品] R441.1[医药卫生—药学]