心理干预对急性冠脉综合征并发焦虑障碍患者血清皮质醇和超敏C反应蛋白的影响  

Effect of Psychological Intervention on Serum Cortisol and High Sensitive C Reactive Protein in Patients with Acute Coronary Syndrome Complicated with Anxiety Disorder

作　　者：林巧芬[1] 刘世明[2] 

机构地区：[1]武警广东省总队医院心血管内科,广东广州510507 [2]广州医科大学附属第二医院心血管内科,广东广州510260

出　　处：《四川医学》2016年第12期1375-1379,共5页Sichuan Medical Journal

摘　　要：目的探讨心理干预对急性冠脉综合征(ACS)并发焦虑障碍患者血清皮质醇、超敏C反应蛋白(hs-CRP)及血糖水平的影响。方法选取本院160例并发焦虑障碍的ACS患者,随机分为两组,对照组给予急性冠脉综合征常规治疗,干预组给予急性冠脉综合征常规治疗联合心理干预,治疗3个月后,对患者进行焦虑评分,并检测两组患者血清皮质醇、超敏C反应蛋白及血糖水平变化。结果治疗3个月后,干预组患者状态焦虑量表评分、血清皮质醇、超敏C反应蛋白及血糖水平均降低,且显著低于治疗前及对照组水平(P<0.05)。结论常规治疗联合心理干预对并发焦虑障碍的ACS患者更有效。Objective To investigate the effect of psychological intervention on serum cortisol,high sensitive C reactive protein（ hs-CRP） and blood glucose levels in patients with acute coronary syndrome（ ACS） complicated with anxiety disorder.Methods 160 cases of ACS patients complicated with anxiety disorder in our hospital were selected and randomly divided into 2groups.Patients in the control group were given conventional treatment of acute coronary syndrome,and the intervention group received conventional therapy of acute coronary syndrome combined withpsychological intervention. After 3 months of treatment,the anxiety score of two groups of patients were detected,and serum cortisol,high sensitivity C reactive protein and change of blood glucose levels were detected.Results After 3 months of treatment,the anxiety scale score,serum cortisol,high sensitivity C reactive protein and blood glucose levels in the intervention group were decreased,significantly lower than those before treatment and those in control group（ P〈0.05）. Conclusion Conventional therapy combined with psychological intervention for patients with anxiety disorders in patients with ACS is more effective.

关 键 词：心理干预 急性冠脉综合征 皮质醇 超敏C-反应蛋白 血糖 状态焦虑量表 

分 类 号：R541.4[医药卫生—心血管疾病]