超声三维斑点追踪技术评价肝硬化患者右心室心肌功能  

Evaluation of right ventricular myocardial function in patients with liver cirrhosis using 3D speckle tracking imaging

作　　者：钱嵘[1] 熊爱民[1] 杨唯衷 王秀梅[1] 刘萍[1] 刘文杰[1] 陈婷婷[1] 周竹[1] 谢艳春[1] 柯晶晶[1] 李晶[1] 徐晓婷[1] 杨峻[2] 

机构地区：[1]解放军第八五医院特诊科,上海200052 [2]解放军第八五医院检验科,上海200052

出　　处：《肝脏》2016年第12期1030-1032,共3页Chinese Hepatology

摘　　要：目的探讨三维斑点追踪技术在评价肝硬化患者右室心肌功能中的应用价值。方法将47例肝硬化患者按照Child-Pugh分级分为A、B、C三组,对照组为30例健康志愿者。应用三维斑点追踪技术(3D-STI)分析各组患者及对照组右心室整体面积应变(GAS)、各节段心肌峰值面积应变(AS)、心肌不同步指数(ASDI)及右室射血分数(RVEF)。结果A组各指标较对照组无明显差异,B组部分心肌节段AS、GAS、ASDI较对照组及A组增加(P<0.05),RVEF较对照组差异无统计学意义,C组部分心肌节段AS、GAS较对照组及A组减低(P<0.05),ASDI较对照组及A组增加(P<0.05),RVEF较对照组及A组明显减低(P<0.05)。结论肝硬化会引起右心室心肌损伤,超声斑点追踪技术可有效评价肝硬化不同阶段右心室心肌功能。Objective To investigate the application value of three-dimensional speckle tracking imaging（3D-STI）in evaluating myocardial function of right ventricle in patients with liver cirrhosis.Methods Forty-seven patients with liver cirrhosis were divided into group A,B and C according to Child-pugh score,and 30 healthy volunteers were enrolled as control group.3D-STI was applied to analyze general area strain（GAS）,area strain（AS）and area strain dyssynchrony index（ASDI）of all myocardial segments in different groups.Right ventricular ejection fraction（RVEF）were measured by echocardiography in all groups.Results There was no significant difference in all indexes between group A and control group.In terms of some myocardial segments,group B showed high levels of GAS,AS and ASDI than control group and group A（P〈0.05）,but no significant difference in RVEF than control group.Group C showed significantly lower levels of GAS,AS and RVEF than control group and group A（both P〈0.05）,but higher level of ASDI（P〈0.05）.ConclusionLiver cirrhosis could lead to myocardial damages of right ventricle,which could be effectively assessed by STI in different stages of liver cirrhosis.

关 键 词：超声心动图 肝硬化 斑点追踪技术 面积应变 三维 

分 类 号：R445.1[医药卫生—影像医学与核医学] R575.2[医药卫生—诊断学]