八月瓜果皮中齐墩果酸的大孔树脂分离工艺  

Separation Technology of Oleanolic Acid in Akebia Trifoliata Peel by Macroporous Resin

作　　者：张晓旭[1] 欧阳玉祝[1] 聂鹏程[1] 唐宁梅 ZHANG Xiaoxu OUYANG Yuzhu NIE Pengcheng TANG Ningmei(College of Chemistry and Chemical Engineering,Jishou University,Jishou 416000, Hunan China)

机构地区：[1]吉首大学化学化工学院,湖南吉首416000

出　　处：《吉首大学学报（自然科学版）》2016年第6期56-61,共6页Journal of Jishou University(Natural Sciences Edition)

基　　金：吉首大学2015年度校级科研项目(15JDY004)

摘　　要：对7种商品化大孔树脂吸附分离八月瓜果皮齐墩果酸的性能进行对比筛选,发现XDA-1型树脂最适合八月瓜果皮齐墩果酸的分离.在单因素实验基础上,用响应面优化法考察了固液比、吸附温度和吸附时间对齐墩果酸提取率的影响.结果表明,在固液比为1∶8(g/mL),40℃温度下吸附315 min,齐墩果酸的提取率为0.265 6%.模型预测值为0.243 2%,实验结果与模型预测值吻合.The separation of Akebia Trifoliata peel oleanolic acid with seven commercial macroreticular resins were studied.The results showed that XDA-1is optimal resin for the separation of Akebia Trifoliata peel oleanolic acid.On the basis of single factor experiments,influences of solid-liquid ratio,adsorption temperature and adsorption time on the oleanolic acid extraction yield were investigated by response surface optimization.The experimental results showed that extraction yield of oleanolic acid is 0.265 6%in solid-liquid ratio for 1∶8（g/mL）,40℃temperature adsorption 315 min.Predictive value of model on oeanolic acid extraction yield was 0.243 2%.Those results conform with the model prediction.

关 键 词：八月瓜 大孔树脂 齐墩果酸 分离 

分 类 号：R284.2[医药卫生—中药学]