Measurement of the Elasticity of Biological Soft Tissue of Finite Thickness  

作　　者：周红生 王彤宇 徐峥 程茜 钱梦騄 刘逍逸 

机构地区：[1]College of Mechanical and Electric Engineering,Changchun University of Science and Technology [2]Shanghai Acoustics Laboratory,Chinese Academy of Sciences [3]Institute of Acoustics,Tongji University

出　　处：《Chinese Physics Letters》2016年第12期96-100,共5页中国物理快报（英文版）

基　　金：Supported by the National Natural Science Foundation of China under Grant Nos 11274342,11304353,11404245 and 11474042

摘　　要：Elasticity is of profound significance to evaluating the function of a biological soft tissue. When the elasticity of a tissue is macroscopically changed, it means that the biological function of the tissue is abnormal and some disease or injury may occur. In the present work, an elastometer is developed to measure the elasticity of biological soft tissues. The measurement is based on the indentation method and the force is measured by the bending of the cantilever. The force-indentation data of the soft tissue is experimentally measured by this elastometer and Young＇s modulus of the tissue is calculated using the Hertz-Sneddon model. For comparison, a numerical model for the indentation method is established using the finite element method. The difference between the actual modulus and the measured modulus is discussed. The effect of the thickness of the specimen on the measurement is investigated. Young＇s moduli of beef, porcine liver and porcine kidney are experimentally measured. The results indicate that our elastometer is effective in measuring Young＇s modulus of a soft tissue quantitatively.Elasticity is of profound significance to evaluating the function of a biological soft tissue. When the elasticity of a tissue is macroscopically changed, it means that the biological function of the tissue is abnormal and some disease or injury may occur. In the present work, an elastometer is developed to measure the elasticity of biological soft tissues. The measurement is based on the indentation method and the force is measured by the bending of the cantilever. The force-indentation data of the soft tissue is experimentally measured by this elastometer and Young＇s modulus of the tissue is calculated using the Hertz-Sneddon model. For comparison, a numerical model for the indentation method is established using the finite element method. The difference between the actual modulus and the measured modulus is discussed. The effect of the thickness of the specimen on the measurement is investigated. Young＇s moduli of beef, porcine liver and porcine kidney are experimentally measured. The results indicate that our elastometer is effective in measuring Young＇s modulus of a soft tissue quantitatively.

关 键 词：of in IS for Measurement of the Elasticity of Biological Soft Tissue of Finite Thickness 

分 类 号：R318.01[医药卫生—生物医学工程]