羊水栓塞诊断的方法学研究进展及法医学意义  

Progress in the research of diagnosis of amniotic fluid embolism based on the methodologies in forensic medicine

作　　者：李文鹤[1,2] 王昊[3] 童昉 梁悦[1] 张琳[1] 周亦武[1] Li Wenhe Wang Hao Tong Fang Liang Yue Zhang Lin Zhou Yiwu(Department of Forensic Medicine, Tongji Medical College of Huazhong University of Science and Technology, Wuhan 430030, China Department of Pathology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030 Forensic Technology Office of Chongqing Municipal Public Security Bereau, Chongqing, 400021, China)

机构地区：[1]华中科技大学同济医学院法医学系,湖北武汉430030 [2]华中科技大学同济医学院附属武汉中心医院病理科,湖北武汉430014 [3]重庆市公安局法医技术室,重庆400021

出　　处：《中国法医学杂志》2016年第6期577-579,共3页Chinese Journal of Forensic Medicine

基　　金：国家自然科学基金面上项目(81273336);"十三五"国家重点研发项目(2016YFC0800701)

摘　　要：羊水栓塞(amniotic fluid embolism,AFE)是指分娩过程中羊水进入母血循环,引起肺栓塞、休克甚至死亡等一系列严重症状的综合征。目前对于AFE的诊断为排除性诊断,方法缺乏灵敏性和特异性。因此随着以AFE为死因的孕产妇病死率的升高,寻找更精确的AFE诊断方法成为了法医学研究的重点。本文结合相关文献概述了AFE诊断方法的研究进展,希望能为法医学鉴定提供方法学参考。Amniotic fluid embolism refers to the accessible amniotic fluid component of maternal circulation leading to a series of severe symptoms, such as pulmonary embolism, shock or even death. Up till now, AFE is a diagnosis of exclusion. The sensitivity and specificity of these methods were poor. With the increasing maternal mortality caused by AFE in forensic medicine, it is important to seeking for more precise diagnosis method. This review intends to provide methodological reference for forensic identification through the research progress of the diagnosis of AFE.

关 键 词：法医病理学 羊水栓塞 诊断 方法学 

分 类 号：D919[医药卫生—法医学]