桥本甲状腺炎超声分型与生化指标的相关性  

Correlation between Hashimoto's thyroiditis ultrasound typing indicators and biochemical

作　　者：李梦灵 赵凯军[1] 葛冠男[2] 邢洁[1] LI Meng-ling ZHAO Kai-jun GE Guan-nan XING Jie(Department of Ultrasonic, China-Japan Union Hospital, Jilin University, Changchun 130033, China)

机构地区：[1]吉林大学中日联谊医院超声科,吉林长春130033 [2]中国医学科学院北京协和医院外科

出　　处：《中国地方病防治》2016年第9期1032-1034,共3页Chinese Journal of Control of Endemic Diseases

摘　　要：目的探讨桥本甲状腺炎（hashimoto thyroiditis,HT）超声图像分型与甲状腺生化指标（TSH、TT_3、TT_4、FT_3、FT_4、TGA、TMA）之间的相关性。方法采用二维彩色多普勒超声诊断仪（探头频率为10MHz,分辨率为1~2mm）对2014年12月-2016年1月期间我院外科收治的150例经病理确诊合并甲状腺占位性病变的HT住院患者进行超声检查,在超声检查的同时,对所有患者进行甲状腺功能生化指标促甲状腺激素（TSH）、三碘甲状腺原氨酸（TT_3）、四碘甲状腺原氨酸（TT_4）、游离三碘甲状腺原氨酸（FT_3）、游离四碘甲状腺原氨酸（FT_4）、甲状腺微粒体抗体（TGA）、甲状腺球蛋白抗体（TMA）的检查;根据超声图像表现,对HT进行超声分型,将HT各超声分型与甲状腺功能指标检测结果进行对比,探讨两者之间的相关性。结果根据超声图像表现,将HT分为：腺体粗糙型、弥漫散在小结节型、弥漫中结节型、弥漫回声减低型、大片状回声减低型及散在大结节伴腺体回声减低型6型;弥漫回声减低型HT患者的TGA、TMA阳性率最低,弥漫中结节型TGA、TMA阳性率最高;FT_3、FT_4、TT_4仅有少数病例降低,TT_3均在正常范围。结论 HT患者各超声分型与其相关甲状腺生化指标具有密切关系,其可用于HT病程各时期的判断指标。Objective To investigate the correlation between the ultrasonic image of Hashimoto thyroiditis（ HT） and thyroid biochemical indexes（ TSH,TT_3,TT_4,FT_3,FT_4,TGA,TMA）.Methods Using two- dimensional color doppler ultrasonic diagnostic apparatus（ 10 MHZ probe frequency,a resolution of 1 ~ 2 mm） from December 2014 to January 2016 in our hospital surgical treatment of 150 cases of pathologically confirmed with thyroid space occupying lesions of HT hospitalized patients with ultrasound,At the same time,ultrasound examination of all patients with thyroid function of biochemical indicators（ Thyroid stimulating hormone TSH,Three triiodothyronine TT_3,Four triiodothyronine TT_4,Three free triiodothyronine FT_3,Free triiodothyronine four FT_4,Thyroid microsomal antibody TGA,Thyroglobulin antibody TMA）.Results According to the ultrasonographic features,HT is divided into： glands rough type,diffuse scattered small nodules type,diffuse nodular type,diffuse echo reduction type,large sheet echo reduction type,scatter in large nodules with glandular echo reduction 6 type.In patients with diffuse echo reduction type TGA,TMA positive rate was the lowest,diffuse nodule type TGA,TMA positive rate was the highest; FT_3,FT_4,TT_4 only a few cases decreased,TT_3 were in the normal range.Conclusion HT patients ultrasonic classification were closely related to the thyroid biochemical indicators,it can be used to determine the course of HT indicators.

关 键 词：桥本甲状腺炎 超声 分型 生化指标 

分 类 号：R581.4[医药卫生—内分泌]