两个3-甲基-2-乙酰吡嗪缩4-苯基氨基脲双核铜(Ⅱ)配合物的晶体结构及与DNA的相互作用（英文）  

Two Binuclear Cu(Ⅱ) Complexes with 1-(3-Methylpyrazin-2-yl)ethylidene-4-phenylsemicarbazide: Crystal Structures and DNA Interaction

作　　者：林龙[1,2] 李先宏[1] 张波[1] 张战营[1] 吴伟娜[3] 王元[3] LIN Long LI Xian-Hong ZHANG Bo ZHANG Zhan-Ying WU Wei-Na WANG Yuan(School of Materials Science and Engineering, Henan Polytechnic University, Jiaozuo, Henan 454000, China School of Mathematics and Informatics, Henan Polytechnic University, Jiaozuo, Henan 454000, China College of Chemistry and Chemical Engineering, Henan Polytechnic University, Jiaozuo, Henan 454000, China)

机构地区：[1]河南理工大学材料科学与工程学院,焦作454000 [2]河南理工大学数学与信息科学学院,焦作454000 [3]河南理工大学化学化工学院,焦作454000

出　　处：《无机化学学报》2017年第1期143-148,共6页Chinese Journal of Inorganic Chemistry

基　　金：国家自然科学基金(No.21001040,21404033,21401046);河南省科技厅基础与前沿项目(No.162300410011);教育厅自然科学基金(No.12B150011,14B150029)资助

摘　　要：合成并通过单晶X射线衍射、元素分析及红外光谱表征了配合物[Cu_2(L)_2Cl_2](1)和[Cu_2(L)_2(OAc)_2](2)的结构(HL为3-甲基2-乙酰吡嗪缩4-苯基氨基脲)。单晶衍射结果表明,2个配合物中,每个拥有四方锥配位构型的Cu(Ⅱ)离子与来自1个阴离子配体L-的N2O电子供体和2个阴离子配位(1中为氯离子,2中为醋酸根离子),其中1个阴离子为μ2桥联配位模式。荧光光谱结果表明,配合物与DNA的相互作用强于配体。Two binuclear complexes, namely[Cu2（L）2Cl2] （1） and[Cu2（L）2（OAc）2] （2） （where HL is 1-（3-methylpyrazin-2-yl）ethylidene-4-phenylsemicarbazide）, have been synthesized and characterized by single crystal X-ray diffraction, elemental analysis and IR spectroscopy. X-ray diffraction analysis results show that in both binuclear complexes, each central Cu（Ⅱ） ion with a distorted square pyramid coordination geometry is surrounded by one independent anionic ligand with N2O donor set and two coordinated anions （chloride for 1, whilst acetate for 2）, one of which acts as a μ2-bridge. In addition, the fluorescence spectra indicate that the interactions of the complexes with DNA are stronger than that of the ligand HL. CCDC：1455421, 1; 1455422, 2.

关 键 词：缩氨基脲 铜配合物 吡嗪 晶体结构 DNA相互作用 

分 类 号：O614.121[理学—无机化学]