开滦研究人群臂-踝脉搏波传导速度的正常值及参考范围  被引量:6

Normal value and reference value range of brachial-ankle pulse wave velocity among Kailuan study population

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作  者:高竞生[1] 宋路 吴云涛[1] 郑晓明[1] 赵晓红[1] 杨静[1] 阮春雨[1] 赵华灵 李春慧 王一鸣 陈朔华[1] 吴寿岭[1] Gao Jingsheng Song Lu Wu Yuntao Zheng Xiaoming Zhao Xiaohong Yang Jing Ruan Chunyu Zhao Hualing Li Chunhui Wang Yiming Chen Shuohua Wu Shouling(Department of Cardiology, Kailuan Hospital, North China University of Science and Technology, Tangshan 063000, Chin)

机构地区:[1]华北理工大学附属开滦总医院心内科,唐山063000 [2]华北理工大学研究生学院

出  处:《中华心血管病杂志》2016年第12期1047-1051,共5页Chinese Journal of Cardiology

摘  要:目的探讨开滦研究人群臂-踝脉搏波传导速度(baPWV)的正常值及参考范围。方法2010至2015年期间参加开滦集团健康体检且完成baPWV检测的职工共22622名,其中体检资料缺失者2000名,以其余20622名职工作为总人群。排除其中有心肌梗死、卒中、糖尿病、高血压病史及正在服用降压药或调血脂药者8788名,并排除吸烟者2725名后,以剩余的9109名职工作为纳入人群,分析baPWV的正常值及参考范围。结果(1)纳入人群男女性之间的年龄、身高、体重、baPWV、收缩压、舒张压、平均动脉压、脉压差、估算肾小球滤过率、总胆固醇、高密度脂蛋白胆固醇、甘油三酯、高敏C反应蛋白和空腹血糖差异均有统计学意义(P均〈0.01)。(2)〈30、30~39、40—49、50~59、60—69和≥70岁男性人群的baPWV均值及95%分位数分别为1248(933~1564)cm/s、1345(995~1696)cm/s、1407(1007—1807)cm/s、1457(987~1927)cm/s、1589(966~2213)cm/s和1898(1018~2778)cm/s;〈30、30—39、40—49、50~59、60—69和I〉70岁女性人群的baPWV均值及95%分位数分别为1080(815~1344)cm/s、1162(845—1480)cm/s、1264(911~1618)cm/s、1386(1004~1768)cm/s、1581(967~2196)cm/s和1874(1288—2459)cm/s。结论不同年龄和性别开滦研究人群的baPWV正常值及参考范围不同。临床试验注册号中国临床试验注册中心,注册号为ChiCTR-TNRC-11001489。Objective To establish the normal and reference values of brachial-ankle pulse wave velocity (baPWV) based on Kailuan study population. Methods There were 22 622 staffs of Kailuan Group who underwent 2010 to 2015 health check-up and baPWV measurement. Data of 20 622 staffs were analyzed after excluding 2 000 staffs due to incomplete data. Of these, 9 109 normal individuals were selected for final analysis of normal and reference values for baPWV after excluding 8 788 staffs who had myocardial infarction, stroke, diabetes, hypertension history, treated by either anti-hypertensive or lipid-lowering drugs, and 2 725 smoker. Results ( 1 ) Age, height, weight, baPWV, systolic pressure, diastolic blood pressure, mean arterial pressure, pulse pressure, estimated glomerular filtration rate, total cholesterol, triglyceride, high density lipoprotein cholesterol, sensitivity C-reactive protein, fasting blood glucose were significant difference between male and female population. (2) In male population, baPWV (mean (rang of 95% ) ) were 1 248(933 - 1 564) cm/s for age 〈30 years, 1 345(995 - 1 696) cm/s for 30 -39 years, 1 407( 1 007- 1 807) ern/s for 40-49 years, 1457(987 -1 927) cm/s for 50 -59 years, 1 589(966 - 2 213) cm/s for 60 - 69 years, 1 898 ( 1 018 - 2 778 ) cm/s for age I〉 70 years; in female population, baPWVv( mean( rang of 95% ) ) were 1 080(815 - 1 344) cm/s for age 〈30 years, 1 162(845 - 1 480) cm/s for 30 -39 years, 1 264(911 -1 618) cm/s for40 -49 years, 1 386(1 004 -1 768) cm/s for50 - 59 years, 1 581(967 -2 196) cm/s for 60 -69 years, 1 874(1 288 -2 459) cm/s for age≥70 years.Conclusion Normal value and rang of baPWV are different in different age and gender among Kailuan study population. Clinical Trail Registry Chinese Clinical Trail Registry, ChiCTR-TNRC-11001489.

关 键 词:参考值 性别特性 年龄因素 臂-踝脉搏波传导速度 

分 类 号:R54[医药卫生—心血管疾病]

 

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