福州地区咽喉反流性疾病的流行病学调查  

Prevalence of laryngopharyngeal reflux disease in Fuzhou region of China

作　　者：陈贤明[1] 李垚[1] 郭文玲[1] 王文涛[1] 鲁明[1] Chen Xianming Li Yao Guo Wenling Wang Wentao Lu Ming(Department of Otorhinolaryngology Head and Neck Surgery, Fu Zhou Hospital, Fuzhou 350025, Chin)

机构地区：[1]南京军区福州总医院耳鼻咽喉头颈外科,350025

出　　处：《中华耳鼻咽喉头颈外科杂志》2016年第12期909-913,共5页Chinese Journal of Otorhinolaryngology Head and Neck Surgery

摘　　要：目的 明确福州地区咽喉反流性疾病（laryngopharyngeal reflux disease,LPRD）的患病率,为制订LPRD的防治措施提供理论依据.方法 采用随机整群抽样的方法对福州地区居民小区4 100名10～70岁的常住居民进行问卷调查.采用Belafsky反流症状指数评分量表（reflux symptom index,RSI）进行调查,并对相关因素进行分析.结果 有效问卷4 063例,RSI评分＞13分为阳性,LPRD患病率为5.00％（203/4 063）.各个年龄段患病率比较差异有统计学意义（P＜0.05）,不同年龄段两两比较,其中30 ～ 39岁年龄段患病率较10 ～ 19岁年龄段高,两组患病率差异有统计学意义（x2=8.532,P=0.003）.男性的LPRD患病率较女性高,两组患病率比较差异有统计学意义（P＜0.05）.不同职业LPRD患病率比较差异有统计学意义（P＜0.05）,其中产业工人患病率7.89％ （24/304）,学生患病率3.14％ （4/196）,两组患病率比较差异有统计学意义（x2=10.947,P＜0.001）.RSI得分与清嗓动作的相关性最大,相关系数为0.687,同时与咽喉堵塞感和咽部异物感呈显著相关.结论 福州地区人群LPRD患病率为5.00％,年龄、性别、职业,以及清嗓动作、咽喉堵塞感、咽部异物感与咽喉反流相关.Objective To assess the prevalence of laryngopharyngeal reflux disease （LPRD） in the Fuzhou region.Methods A total of 4100 subjects who aged from 10 to 70 years derived from a random cluster sampling in fourty districts of Fuzhou region and they were asked to complete questionnaires.According to the grade standard of reflux symptom index （RSI）,subjects with total score more than 13 were defined as having LPRD.The factors associated with LPRD were evaluated with corrective analysis.Results Effective questionnaires were obtained from 4 063 of 4 100 subjects.The prevalence of LPRD was 5.00% （203/4 063）.The prevalence of LPRD in subjects of 30-39 years old was significantly higher than that in subjects of 10-19 years old （x2 =8.532,P =0.003）.The prevalence of LPRD in men was higher than that in women （P 〈 0.001）.There were significant difference in the prevalence of LPRD between different occupations （P 〈 0.001）.The prevalence of LPRD in industrial workers was 7.89% （24/304）,higher than that in students （4/196,3.14%）.RSI was correlated with clearing throat,with a correlation coefficient of O.687.LPRD was also correlated with dysphagia and pharyngeal foreign body sensation.Conclusions The prevalence of LPRD in Fuzhou region is 5.00% and LPRD is closely related to age,sex,occupation,clearing throat,dysphagia and pharyngeal foreign body sensation.

关 键 词：喉咽反流 流行病学 体征和症状 

分 类 号：R766.5[医药卫生—耳鼻咽喉科]