某院门诊超说明书用药情况分析  

Analysis of off-label Drug use in Outpatient Department of Our Hospital

作　　者：陆昊[1] 夏海建[1] 蒋倩[1] 黄富宏[1] LU Hao XIA Haijian JIANG Qian HUANG Fuhong(Department of pharmacy, First people＇s hospital of Yangzhou, Yangzhou, Jiangsu 225009, Chin)

机构地区：[1]扬州市第一人民医院药剂科,江苏扬州225009

出　　处：《今日药学》2016年第11期816-818,共3页Pharmacy Today

摘　　要：目的分析某院门诊超说明书用药情况,探讨超说明书用药的合理性。方法从该院门诊2016年1月~7月处方中,每月随机抽取1 d处方,以药品说明书为依据,对超说明书用药进行登记并分类统计分析。结果共抽取处方7 326张,其中超说明书用药处方743张,占10.1%,超说明书用药频次837次。超说明书用药情况多见于超给药途径（33.1%）、超适应证（27.6%）、超给药频次（25.7%）等方面。结论该门诊超说明书用药情况普遍存在,其合理性和科学性大多有文献支持,但也存在部分不合理用药的情况。OBJECTIVE To analyze the off-label drug use of outpatient department in our hospital and to discuss the reasonability of off-label drug use. METHODS The prescriptions of a day in a month were collected randomly from our hospital outpatient prescription between January and July in 2016. The off-label drug use was registered,classified and statistical analyzed based on Drug Instructions. RESULTS A total of 7326 prescriptions were extracted,743 prescriptions of which were off-label drug use,accounting for 10.1%,and the off-label drug use frequency was 837 times. The off- label drug use was usually seen in the over routes of administration（ 33.1%）,over indications（ 27. 6%）,over medication frequency（ 25. 7%） and so on. CONCLUSION Off-label drug use is widely existed in outpatient department of our hospital. Its rationality and scientificity is mostly supported by literature. But there are also some cases of irrational drug use.

关 键 词：超说明书用药 适应证 合理用药 

分 类 号：R969.3[医药卫生—药理学]