眼底荧光血管造影在老年糖尿病视网膜病变早期诊断中的应用价值  

The value of fundus fluorescein angiography(FFA)in the early diagnosis of elderly diabetic retinopathy(DR)

作　　者：王文奇[1] 柏清[1] 戴常明[1] 刘庆淮[2] 

机构地区：[1]南京医科大学附属淮安市第一人民医院眼科,江苏淮安223300 [2]南京医科大学第一附属医院眼科,江苏南京210029

出　　处：《中国实验诊断学》2016年第12期2009-2011,共3页Chinese Journal of Laboratory Diagnosis

基　　金：江苏省科学技术厅临床医学科技专项-重点病种的规范化诊疗研究(BL2014089)

摘　　要：目的探讨眼底荧光血管造影(FFA)对老年糖尿病视网膜病变(DR)的早期诊断价值。方法选取360例老年2型糖尿病患者720只眼分别采用检眼镜和FFA检查,比较分析两种检查方法对老年DR早期检出率、不同分期检出率和诊断结果。结果检眼镜对DR的检出率为69.2%,显著低于FFA的90.4%(P<0.01),检眼镜对DR的漏诊率为23.5%;检眼镜对DR分期在Ⅰ期、Ⅱ期和Ⅵ期的检出率显著低于FFA(P<0.05或P<0.01);FFA对检眼镜诊断DR修正率为52.4%。结论 FFA对老年DR早期诊断较为敏感,能够更加可靠、精准地对DR病变程度进行评估,诊断正确率高,可为临床早期治疗提供可靠的客观依据。Objective To discuss the clinical value of FFA in the early diagnosis of elderly DR.Methods 360 elderly patients 720 eyes with T2DM were given ophthalmoscope and FFA examination,then the early detection rate,different staging detection rate and diagnosis results were contrasted between the two methods.Results Detection rate of DR by ophthalmoscope was 69.2%,significantly lower than 90.4% by FFA（P〈0.01）,and the rate of missed diagnosis of DR by ophthalmoscope was 23.5%;detection rate of DR by ophthalmoscope in phase I,phase II,phase VI were significant-ly lower than FFA（P〈0.05 or P〈0.01）;correction rate of FFA for the diagnosis of DR ophthalmoscope was 52.4%. Conclusion FFA is more sensitive in the early diagnosis of elderly DR,it can evaluate DR severity more reliable and ac-curate,has high rate of correct diagnosis.It can provide a reliable obj ective basis for clinical early treatment,early to give the corresponding intervention measures,to protect the patient visual function,improve the quality of life of the pa-tients.

关 键 词：荧光血管造影 糖尿病视网膜病变 早期诊断 

分 类 号：R587.2[医药卫生—内分泌] R774.1[医药卫生—内科学]