急性冠脉综合征的中医证候分布规律研究  

Distribution Regularity of TCM Syndromes in Acute Coronary Syndrome

作　　者：牛子长[1] 付姝菲[2] 毛浩萍[3] 

机构地区：[1]天津中医药大学第一附属医院,天津300193 [2]天津中医药大学,天津300193 [3]天津中医药大学中医药研究院,天津300193

出　　处：《辽宁中医杂志》2016年第12期2488-2491,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：国家自然科学基金项目(81303247);教育部高等学校博士学科点专项科研基金(20121210120009)

摘　　要：目的:揭示急性冠脉综合征的中医相关证候的分布规律,为其临床治疗和相关科研实践提供可靠依据。方法:全面检索近20年来中国期刊全文数据库的急性冠脉综合征中医证候相关文献,统计分析其中医证素、证型规律。结果:共纳入73篇文献,总病例数9506例。急性冠脉综合征证候分布以心血瘀阻、气虚血瘀、痰阻心脉、气虚痰瘀、气阴两虚、气阴两虚血瘀、痰瘀互结、心气不足、气滞血瘀、气滞心胸等为常见证型,多见证素为血瘀、痰浊、气虚、阴虚、阳虚、气滞。气虚为本虚中首位,阴虚、阳虚次之;标实中以血瘀为首,气滞、痰浊次之。而在急性冠脉综合征中急性心梗的虚实夹杂证候明显较不稳定心绞痛增多;同时急性心梗中瘀血、痰浊证素所占的比例也明显多于不稳定心绞痛。结论:急性冠脉综合征是以本虚标实为其病机,本虚以气虚、阴虚为主,标实以血瘀、痰浊、气滞最为常见。而随着疾病严重程度的增加,虚实夹杂证候及瘀血、痰浊证素都随之增加,提示中医对急性冠脉综合征的防治在标本兼顾的基础上尤其应该注重对瘀血、痰浊证的防治。Objective ： To reveal the distribution regnlarity of TCM syndromes in acute coronary syndrome and provide the relevant evidence for clinical practice and scientific research by studying the relevant literature. Methods ： The relevant literature in the last 20 years of acute coronary syndrome in Chinese journal full text database was searched and the distribution of TCM syndromes types and syndrome elements were statistically analyzed. Results ： Seventy - three cases were included and the total number was 9506. The common syndromes in patients with acute coronary syndrome were blood stasis, qi deficiency and blood stasis, stagnation of phlegm in heart meridian, qi deficiency and phlegm stasis, deficiency of both qi and Yin, deficiency of both qi and Yin with blood stasis, phlegm and blood stasis, heart qi deficiency, qi stagnation and blood stasis, qi stagnation in heart, etc. The related factors were blood stasis, phlegm - turbidity, qi deficiency, Yin deficiency, Yang deficiency and qi stagnation. Of the Ben - root deficiency type, qi deficiency was the first, Yin deficiency and Yang deficiency were the two following factors. In the Biao - symptom excess type, blood stasis was the first and phlegm -turbidity and qi stagnation were the followed factors. In patients with acute coronary syndrome, acute myocardial infarction was significantly higher than that of unstable angina. The proportions of blood stasis and phlegm turbidity syndrome in acute myocardial infarction were more than that in unstable angina. Conclusion：Types of TCM syndrome and element distribution in acute coronary syndrome indicate that its pathogenesis is Ben -root deficiency and Biao - symptom excess. Qi deficiency and Yin deficiency were commonly seen in Ben- root deficiency type and blood stasis, phlegm - turbidity, qi stagnation were commonly seen in Biao -symptom excess type. And with the severity of the disease increasing, blood stasis and phlegm - turbidity syndrome elements were increased. It is a hint that prevention and treatme

关 键 词：急性冠脉综合征 中医证候 证候要素 分布规律 

分 类 号：R541.4[医药卫生—心血管疾病]