益肾健脾法治疗早期先兆流产合并亚临床甲状腺功能减退的初步研究  

Method of Benefiting Kidney and Spleen Treats Early Threatened Abortion with Subclinical Hypothyroidism

作　　者：赵薇[1] 陆源源[2] 詹群[1] 李苗苗[1] 任庆龄 陈盛君[3] 季露[3] 

机构地区：[1]南京市中医院妇科,江苏南京210001 [2]南京市中医院内分泌科,江苏南京210001 [3]南京中医药大学,江苏南京210029

出　　处：《辽宁中医杂志》2016年第12期2575-2578,共4页Liaoning Journal of Traditional Chinese Medicine

基　　金：南京市医学科技发展项目(YKK13098)

摘　　要：目的:在以往研究取得良好疗效的基础上,通过监测早期先兆流产合并亚临床甲状腺功能减退患者体内血清TSH的变化为主线,观察临床疗效、血清FT4、TPOAb的变化、胚胎发育情况,并随访妊娠结局。方法:选取早期先兆流产合并亚临床甲状腺功能减退60例,随机分为中药治疗组31例和优甲乐对照组29例。分别观察两组治疗前后血清TSH、FT4、TPOAb变化情况,追访妊娠的结果。结果:治疗组保胎成功率为90.32%%,对照组89.66%,两组比较经统计分析无显著性差异。治疗后两组患者血清TSH水平均呈下降趋势,治疗组和对照组治疗前后相比有显著性差异;组间差异无统计学意义。结论:益肾健脾法治疗早期先兆流产合并亚临床甲状腺功能减退疗效显著,可以改善患者甲状腺功能。Objective：On the basis of previous studies, to further explore and discuss the changeable rules of data about early threatened abortion patients with subclinical hypothyroidism, including the changes of serum TSH, serum FT4 and TPOAb, the conditions of embryo growth and the outcomes of pregnancy. Methods ： Sixty early threatened abortion patients with subclinical hypothyroidism were divided into two groups randomly that 29 cases participated in Chinese medicine treatment group and 31 cases of control group with Levothyroxine Sodium Tablets. The changes of serum TSH, FF4, TPOAb and the pregnancy outcome were observed in the two groups before and after treatment. Results ：The success rate of tocolysis was 90.32% in treatment and 89.66% in the control. There was no significant difference between the two groups by statistical analysis. Besides, after treatment, the serum TSH level of the two groups was decreased and so there were significant differences between the treatment group and the control group. But the difference between groups was not statistically significant. Conclusion：The clinical effect of benefiting kidney and spleen method for early threatened abortion with subclinical hypothyroidism was significant because it can improve patients＇ thyroid function.

关 键 词：先兆流产合并亚临床甲状腺功能减退 益肾健脾法 中医药疗法 妊娠结局 

分 类 号：R714.21[医药卫生—妇产科学]