242例胆道手术患者胆汁成分与胆石成因研究  

Study of bile composition and causes of gallstone in 242 cases of biliary surgery

作　　者：辜天慧[1] 

机构地区：[1]巴中市中心医院普外科,四川巴中636000

出　　处：《川北医学院学报》2016年第6期838-840,共3页Journal of North Sichuan Medical College

基　　金：四川省医学科研青年创新课题(Q15087)

摘　　要：目的：研究胆道手术患者的胆汁成分与胆石形成的可能原因。方法：回顾性分析242例胆道手术病例的临床资料,统计分析其胆汁成分与其他生化检测数据。结果：1胆结石患病率女性显著高于男性;2年龄分布以40-60岁组最多;3病种以结石性慢性胆囊炎居首;4结石性质主要为胆固醇结石或胆固醇为主的混合结石;5胆固醇结石患者胆汁胆固醇、甘油三酯含量及腹壁脂肪厚度显著高于胆色素结石患者,组间比较具有统计学差异（P〈0.05）;6胆色素结石主要为胆道细菌感染后形成。结论：胆结石患者具有明显的性别、年龄等特征;胆固醇高易发胆固醇石,不易发生色素石,可能与胆固醇有易溶解胆色素的作用有关。Objective ：To study of bile composition and causes of gallstone in patients with biliary surgery. Methods ： Retrospective analysis of clinical data of 242 cases with biliary tract surgery, statistical analysis of the composition of bile and other biochemical detection data. Results：The prevalence of gallstones in female is significantly higher than male,40 -60 age group is the most with age distribution. Gallstone with chronic cholecystitis is the most in all cases,cholesterol stone and mixed stones are mainly by stone nature. Biliary cholesterol and triglyceride levels and abdominal fat thickness with cholesterol stone patients are significantly higher than that of patients with bile pigment calculus ,there are statistically difference between groups （P 〈 0.05 ） , bile pigment calculus is mainly due to biliary tract bacterial infections. Conclusion：Patients with gallstones have obvious features such as gender,age. High cholesterol is used cholesterol stone,are less pigment stone,may be associated with cholesterol are easy to dissolve the role of bile pigment.

关 键 词：胆结石 胆汁成份 胆石成因 

分 类 号：R657.4[医药卫生—外科学]