地塞米松预防全髋置换术后恶心呕吐的疗效观察  

Effect of dexamethasone on preventing postoperative nausea and vomiting after total hip replacement

作　　者：肖忠军[1] 王宏伟[1] 焦富荣 

机构地区：[1]泰兴市第三人民医院麻醉科,江苏泰兴225400

出　　处：《安徽卫生职业技术学院学报》2016年第6期55-56,共2页Journal of Anhui Health Vocational & Technical College

摘　　要：目的:观察地塞米松联合昂丹司琼预防全髋置换术后恶心呕吐(PONV)的疗效,分析其可行性和有效性。方法:选择拟行全髋置换术的100例患者作为本研究对象,随机分为对照组(I组,50例)和观察组(II组,50例)。I组麻醉诱导前静脉注射地塞米松10mg;II组麻醉诱导前静脉注射地塞米松10mg和手术结束前30min静脉注射昂丹司琼4mg。观察两组患者术后24h和48h内恶心呕吐的发生情况。结果:II组患者术后24h和48h内恶心呕吐的发生率明显低于I组,差异有统计学意义(P<0.05)。结论:地塞米松联合昂丹司琼应用于全髋置换术后,能有效降低术后恶心呕吐的发生率。Objective：To observation the effect of ondansetron combined with dexamethasone in the prevention of PONV after total hip replacement,and toanalyze its feasibility and effectiveness.Methods：All of 100patientstreated with total hip replacement,were randomly divided into control group（Igroup）and observation group（IIgroup）, 50 patients in every group. The incidence of postoperative nausea and vomiting in two groups was observed after operation in 24 hours and 48 hours.Results：The incidences of PONV in II group ,after operation in 24 hours and 48 hours, were significantly lower than those in I group, the differences were statistically significant （ P〈 0.05 ） . Conclusion：Dexamethasone and ondansetron used in total hip replacement,can effectively prevent postoperative nausea and vomiting.

关 键 词：地塞米松 全髋置换术 术后恶心呕吐 

分 类 号：R614[医药卫生—麻醉学]