320排CT低碘浓度联合低管电压在冠脉成像中的应用研究  

Application Research on Low-Tube-Voltage Coronary Computed Tomography with Low Concentration Iodinated Contrast Media by 320-Slice CT

作　　者：方玉荣[1] 申云霞[1] 娄明武[1] 鲁琳[1] 潘雪娜[1] 

机构地区：[1]深圳市龙岗中心医院,广东深圳518116

出　　处：《北华大学学报（自然科学版）》2017年第1期74-78,共5页Journal of Beihua University（Natural Science）

基　　金：深圳市科技创新委项目(JCYJ20140411150309468);深圳市卫生计生系统科研项目(201401095);深圳市发改委项目(CXZZ20140505091419405;2014992)

摘　　要：目的探讨320排螺旋CT低管电压技术联合低碘浓度在冠状动脉成像中的可行性.方法将40例疑似冠心病患者随机分为两组,使用东芝320排螺旋CT进行冠状动脉扫描,分别对两组图像质量进行主观和客观评分,对比有效辐射剂量及碘摄取量.结果 A,B两组的有效辐射剂量及碘摄入量比较差异具有统计学意义(P<0.05),B组患者有效辐射剂量低于A组,且有效辐射剂量较A组降低72.95%,B组患者有效碘摄入量较A组减少18.29%,两组图像噪声值、左冠脉开口处强化CT值差异具有统计学意义(P<0.05),B组图像噪声高于A组,两组图像质量主观评分比较差异无统计学意义(P>0.05).结论 320排螺旋CT冠状动脉成像采用"双低"扫描方案能降低有效辐射剂量和碘摄入量.Objective To investigate the feasibility of the scan protocol using low-tube-voltage and low concentration iodinated media in 320-slice CT coronary angiography. Method 40 patients with suspected or known coronary heart disease who underwent coronary CTA（ CCTA） with a 320-MDCT scanner were divided into two groups randomly.Images were scored subjectively and objectively,and radiation dose and iodine intake were compared.Results The effective dose（ ED） and iodine intake exhibited significant differences between the two groups（ P〈0.05）,and the values in group B were less than those in group A.The ED in group B was reduced by72.95%,compared with that in group A. Accordingly,the amount of iodine in group B was reduced by 18.29%.Statistically significant differences in image noise and CT values of LCR were found between group A and B（ P〈0.05）; in addition,image noise in group B were higher than that in group A.However,the SNR,CNR and image quality scores were comparable to both groups.Conclusion It＇s not only maintaining the image quality but also effectively reducing the amount of radiation dose and iodine intake to use ＂dual low ＂ scanning protocol in coronary angiography with 320-row CT.

关 键 词：320排螺旋CT 冠状动脉成像 双低剂量 辐射剂量 碘摄入量 

分 类 号：R816.2[医药卫生—放射医学] R54[医药卫生—临床医学]