Elafin与皮肤疾病  

Elafin and some skin diseases

作　　者：许秋云[1] 纪超[1] 程波[1] XU Qiuyun JI Chao CHENG Bo.(Department of Dermatology, The First Hospital of Fujian Medical University, Fuzhou 350005, Chin)

机构地区：[1]福建医科大学附属第一医院皮肤科,福州350005

出　　处：《中国麻风皮肤病杂志》2016年第12期760-762,共3页China Journal of Leprosy and Skin Diseases

摘　　要：Elafin是中性粒细胞弹力蛋白酶(neutrophil elastase,NE)的内源性特异性抑制物,通过拮抗NE作用发挥其抗增殖、抗炎症等作用。Elafin参与黑素瘤、银屑病、血管炎、移植物宿主病等多种皮肤疾病的发生发展。本文就Elafin在某些皮肤疾病中的作用加以综述。Elafin is an endogenous specific inhibitor of neutrophil elastase （ NE） which displays anti-proliferation and anti-inflammatory properties by antagonizing NE. Elafin plays a significant role in multiple skin diseases such as melanoma, psoriasis, vasculitis, graft versus host disease, etc. In this paper the role of elafin in some skin diseases is reviewed.

关 键 词：中性粒细胞 弹性 蛋白酶 

分 类 号：R751[医药卫生—皮肤病学与性病学]