血清胱抑素C对老年人冠心病的预测价值  

Predictive value of serum cystatin C in the detection of coronary artery disease among elderly persons

作　　者：陈广胜[1] 韦伟[1] 徐崇利[1] 

机构地区：[1]南京市江宁医院心内科,江苏南京211100

出　　处：《现代医学》2016年第11期1583-1586,共4页Modern Medical Journal

摘　　要：目的：评估血清胱抑素C（Cys C）对老年人冠心病的预测价值。方法：入选167例行冠脉造影检查的60岁以上老年人,分为冠心病组113例和无冠心病的对照组54例。测定受试者的血清Cys C水平,分析其与冠心病的关联性。结果：冠心病组血清Cys C水平显著高于对照组（P〈0.05）。Logistic回归分析显示,Cys C是冠心病的预测因子（OR=11.439,95%CI为1.583-82.688,P〈0.05）。受试者工作特征曲线分析显示,曲线下面积为0.622（95%CI为0.529-0.716,P〈0.05）。结论：血清Cys C是老年人冠心病的预测因子,对老年人冠心病有中等度的预测价值。Objective： To assess the predictive value of serum cystatin C （Cys C） in detecting coronary artery disease（CAD） among elderly persons. Methods： According to the results of coronary angiography, 167 subjects aged over 60 years were divided into two groups ： CAD group （ n = 113 ） and control group （ n = 54）. The relationship between the level of Cys C and CAD was analyzed. Results： Serum Cys C levels in the subjects with CAD were significantly higher than those without CAD（ P 〈 0.05 ）. Logistic regression analysis demonstrated that Cys C was one of the predictors of CAD（ OR = 11. 439,95% CI： 1. 583 - 82. 688, P 〈 0. 05 ）. Receiver operating characteristics analysis showed that the area under the curve was 0.622（95% CI：0.529 -0.716, P 〈0.05）. Conclusion： The level of serum Cys C is associated with the presence of CAD in elderly, which has a moderate predictive value.

关 键 词：胱抑素C 冠心病 老年人 

分 类 号：R541.4[医药卫生—心血管疾病]