亚低温治疗在心肺脑复苏中的应用与研究进展  

Application and research progress of mild hypothermia in cardiopulmonary cerebral resuscitation

作　　者：袁伟[1] 李春盛[1] 

机构地区：[1]首都医科大学附属北京朝阳医院急诊科,北京市心肺脑复苏重点实验室,北京100020

出　　处：《中华危重病急救医学》2016年第12期1165-1169,共5页Chinese Critical Care Medicine

基　　金：北京市科技计划项目（BZ20370）

摘　　要：脑复苏是高级心肺脑复苏（CPCR）中的关键目标。保护心搏骤停（CA）后的脑功能，对于提高患者生存率和出院存活率有着至关重要的意义。亚低温治疗是目前唯一可能改善CA患者复苏后神经功能的有效方法，2010年心肺复苏（CPR）和心血管急救指南已明确推荐亚低温治疗作为成功复苏后昏迷患者的治疗策略之一。尽管目前已有多种实施亚低温的方法，但各有长短，选择上仍存有大量争议，需要进一步研究探讨。现通过对亚低温治疗的作用机制、亚低温治疗不同阶段可能发生的并发症以及亚低温的临床应用，如亚低温治疗前评估、治疗方案选择、降温方法等方面进行总结分析，为临床亚低温治疗提供指导。The cerebral resuscitation is the most important aim in advanced cardiopulmonary cerebral resuscitation （CPCR）. Cerebral function protection after cardiac arrest （CA） is important to improve survival rates including those after the discharge. Therapeutic mild hypothermia maybe the only method that can improve neurological function of patients following resuscitation after CA, which was recommended as one of treatment strategies for unconscious patients after successful resuscitation in 2010 American Heart Association Guidelines for Cardiopulmonary Resuscitation and Emergency Cardiovascular Care. Although there are many cooling methods of inducing hypothermia, each has some advantages or shortcomings. There were many controversies on the choice, which need further research. We make a summary and analysis about the mechanism of therapeutic mild hypothermia, the possible complications at different stages and the clinical application of mild hypothermia, such as the evaluation before therapeutic mild hypothermia and the choice of hypothermia protocol and cooling methods, to provide guidance for clinical mild hypothermia therapy.

关 键 词：心搏骤停 心肺脑复苏 亚低温 神经系统预后 

分 类 号：R459.7[医药卫生—急诊医学]