大学生男男性行为者对暴露前预防HIV感染的接受意愿及影响因素  

Analysis of willingness and influencing factors for usage of pre-exposure prophylaxis among male u-niversity students who have sex with men

作　　者：韦所苏[1] 韦挥德[1] 黄晓红[1] 潘洪平[1] 谭毅[1] 杨光和[1] 刘京虹[1] 吕文娟[1] 韦颖[1] 蓝斯琪[1] 刘慧[1] 吴腾燕[2] 

机构地区：[1]广西壮族自治区人民医院,南宁530021 [2]广西壮族自治区疾病预防控制中心,南宁530028

出　　处：《中华行为医学与脑科学杂志》2016年第12期1128-1132,共5页Chinese Journal of Behavioral Medicine and Brain Science

基　　金：广西壮族自治区卫计委自筹经费科研课题（Z2014625,Z2016448）;广西壮族自治区疾病预防控制中心科技创新课题（GXCDCCK-011）

摘　　要：目的：了解广西大学生男男性行为者（ Men who have sex with men，MSM）对暴露前预防（Pre-exposure prophylaxis，PrEP） HIV 感染的接受意愿及其影响因素。方法采用滚雪球法招募295名大学生MSM，采用自填式问卷进行调查。问卷内容包括人口学信息、性行为特征、对 PrEP 的接受意愿等。采用单因素及多因素Logistic回归进行分析。结果295名大学生MSM中共有58（19．7％）人听说过PrEP，有265（89．8％）人表示愿意接受 PrEP。多因素分析结果显示，通过朋友介绍性伴（ OR＝11．419，95％CI：1．363～95．641）、如PrEP有效，会建议朋友使用（ OR＝87．946，95％CI：13．660～566．222），关心PrEP 获得的方便性（ OR＝119．652，95％CI：3．765～3802．184），表示会坚持每天服药（ OR＝88．245，95％CI：10．237～760．696）是大学生MSM接受PrEP 的促进因素；坚持使用安全套对方会生气（ OR＝0．106，95％CI：0．019～0．606），表示关心PrEP的效果（ OR＝0．010，95％CI：0．001～0．112）是大学生MSM接受PrEP的限制因素。结论大学生MSM对PrEP的接受意愿较高，药物的安全性及服药的方便性是影响其接受PrEP的主要因素，应加强PrEP在大学生MSM中的宣传力度。Objective To analyze the willingness and influencing factors for usage of pre-exposure prophylaxis（PrEP） among male students who have sex with men （MSM） in universities of Guangxi. Meth-ods 295 MSM students in universities were recruited by Snow-balling methods. Questionnaires were self-administered to collect social demographic information,AIDS related risky sexual behaviors and willingness for usage of PrEP. Logistic regression was employed for univariate and multivariate analysis. Results Of the 295 MSM,58（19.7%）had ever heard PrEP,265（89.8%） said that they would like to use PrEP. Multivari-ate logistic regression analysis showed that those who had found partners through friends （ OR=11.419,95%CI：1.363~95.641）, those who would advise his friend to use PrEP （ OR=87.946,95%CI：13.660-566. 222）,those who concerned the convenience to gain the medicine （ OR=119.652,95%CI：3.765-3802.184） and those who said that they could take medicine every day （ OR=88.245,95%CI：10.237-760.696） were more likely to accept PrEP. The subjects whose partners would be angry if they stick to use condoms（ OR=0.106,95%CI：0.019-0.606）,and those who suspected the effectiveness of drugs（ OR=0.010,95%CI：0. 001-0.112） were less likely to accept PrEP. Conclusion The acceptability of PrEP is high in university＆amp;nbsp;students＆#39;MSM. The safety of drugs and the convenience to gain the medicine are the main influencing factors for usage of PrEP.Using of PrEP should be strengthened to the MSM.

关 键 词：艾滋病病毒 大学生 男男性行为者 暴露前预防 接受意愿 

分 类 号：R512.91[医药卫生—内科学]