羧甲基壳聚糖水凝胶的制备研究  

Study on Preparation of Carboxymethyl Chitosan Hydrogel

作　　者：谭福能[1] TAN Funeng(School of Chemistry and Engineering, Wenshan University, Wenshan Yunnan 663099, Chin)

机构地区：[1]文山学院化学与工程学院,云南文山663099

出　　处：《文山学院学报》2016年第6期21-24,共4页Journal of Wenshan University

基　　金：云南省科技厅应用基础研究青年项目"新型壳聚糖衍生物智能凝胶的制备技术研究"(2012FD058)

摘　　要：以壳聚糖为原料,通过改性制得亲水性的羧甲基壳聚糖,并对改性条件进行了研究。采用戊二醛交联法制备羧甲基壳聚糖水凝胶(CMCS-GA)。对该凝胶的成胶条件、p H敏感性和温度敏感性进行了研究。结果表明:羧甲基壳聚糖水凝胶的成胶过程受到了羧甲基壳聚糖浓度、温度、时间、交联剂浓度的影响。所制得的羧甲基壳聚糖水凝胶具有良好的温度和p H响应性。The hydrophilic carboxymethyl chitosan（CMCS） is obtained from chitosan and carboxymethylchitosan hydrogel is prepared by cross-linking of glutaral. The gelation conditions, p H-sensitivity and temperaturesensibility of CMCS hydrogel are studied. The results shows that gelation of CMCS hydrogel is under the influence of the concentration of CMCS, concentration of crosslinking agent, temperature and response time. The CMCS hydrogel shows good p H-sensitivity and temperature sensibility.

关 键 词：壳聚糖 羧甲基壳聚糖 水凝胶 溶胀率 

分 类 号：O648.17[理学—物理化学]