用于与全二维气相色谱联用的高通量飞行时间质谱仪的研制  

Development of High Acquisition Speed Time-of-Flight Mass Spectrometer for Combination with Comprehensive Two-dimensional Gas Chromatography

作　　者：吴曼曼[1,2] 岑延相 杨丽华[3] 乔佳 高伟[1] 

机构地区：[1]暨南大学质谱仪器与大气环境研究所,广州510632 [2]广州禾信仪器股份有限公司,广州510530 [3]北京东西分析仪器有限公司,北京102308

出　　处：《分析化学》2016年第11期1786-1792,共7页Chinese Journal of Analytical Chemistry

基　　金：国家863计划(No.2014AA06A501);广州市珠江科技新星专项(No.201610010149)资助~~

摘　　要：研制了可与全二维气相色谱联用的高通量飞行时间质谱仪,并进行了性能水平测试。设计采用新型高灵敏度电子轰击源及具有垂直引入、双推斥脉冲、二级反射式结构的飞行时间质量分析器,结合高于20 kHz的推斥频率,可获得质量范围1-1000 amu,质量分辨〉1000（m/z 219,ADC采集卡）,检出限低于1 pg,线性动态范围超过4个数量级,同时最快可达400谱/s的高采集速度,完全满足全二维气相色谱与飞行时间质谱联用的检测要求。与一款完全国产化的全二维气相色谱仪联用,实现对石油、香精、环境等多个领域复杂样品的分析,获得令人满意的检测结果,显示了此质谱仪器与全二维气相色谱联用的适用性及其在复杂样品体系全组分分析中的应用潜力。A novel time-of-flight mass spectrometer which adopted high sensitivity electron impact ionization source and orthogonal-injected two-stage-reflector mass analyzer structure was developed for the combination with comprehensive two-dimensional gas chromatography. With 20 kHz of extraction frequency,the mass detection range and mass resolution of this instrument were from 1 to 1000 amu and better than 1000（m / z =219,ADC card）,respectively,with a detection limit of less than 1 pg and a linear range more than 4 orders of magnitude. Meanwhile the instrument has a high acquisition speed of 400 spectra per second,which made it satisfy for combination with comprehensive two-dimensional gas chromatography. For the moment,this mass spectrometer combined with the first domestic comprehensive two-dimensional gas chromatography was successfully used for the detection of many complicated samples in the field of petroleum,environment and essence,revealing its ability for connecting with the comprehensive two-dimensional gas chromatography and the application potential for full component analysis of complex system.

关 键 词：飞行时间质谱 高通量 电子轰击源 全二维气相色谱 

分 类 号：TH843[机械工程—仪器科学与技术]