妊娠期糖尿病对妊娠分娩结局的影响  

Influence of gestational diabetes mellitus on pregnancy and delivery outcomes

作　　者：陈小伟[1,2] 王念跃[2,3] 

机构地区：[1]南京市六合区人民医院,211500 [2]东南大学医学院,南京210009 [3]南京市第二医院,210009

出　　处：《国际检验医学杂志》2017年第1期66-67,70,共3页International Journal of Laboratory Medicine

摘　　要：目的探讨妊娠期糖尿病(GDM)对于妊娠分娩结局的影响。方法选取2014年1月至2015年10月在南京六合区人民医院产检并分娩的孕妇,根据其在妊娠24~28周行75g葡萄糖耐量试验(OGTT)结果,将278例GDM孕妇设为GDM组,同期选取278例健康孕妇作为对照组,并对2组孕妇妊娠分娩结局进行统计分析及比较。结果 GDM组孕妇的OGTT 3个时间点的血糖[空腹血糖(FPG)、服糖后1h(1hPG)、服糖后2h(2hPG)]值分别为(5.08±0.56)、(9.22±1.71)、(7.62±1.48)mmol/L,均高于对照组孕妇OGTT 3个时间点的血糖值,分别为(4.45±0.43)、(7.76±1.35)、(6.34±0.96)mmol/L,差异均具有统计学意义(P<0.05);GDM组妊娠期高血症、胎膜早破、早产、胎儿窘迫、产后出血、巨大儿发生率及剖宫产率均高于对照组,差异有统计学差异(P<0.05)。结论 GDM对妊娠结局有较大影响,可导致母婴严重的并发症,应加强妊娠期糖代谢监测及相关知识的宣教以改善母婴结局。Objective To explore the influence of gestational diabetes mellitus（GDM）on pregnancy and delivery outcomes.Methods 278 pregnant women with GDM were chosen as experimental group who underwent their antenatal care and delivery in Liuhe People′s Hospital in Nanjing,according to the 75 g oral glucose tolerance test（OGTT）performed in pregnant women at 24-28 pregnancy weeks from January 2014 to October 2015.Meanwhile,the other 278 healthy women were chosen as control group.The pregnancy and delivery outcomes of the two groups were compared.Results The 24-28 weeks′3time-point OGTT blood glucose（FPG,1hPG and 2hPG）（mmol/L）values of experimental group were 5.08±0.56,9.22±1.71 and 7.62±1.48 respectively,which were significant higher than that of control group：4.45±0.43,7.76±1.35,6.34±0.96（P〈0.05）.The incidences of pregnancy-induced hypertension syndrome,premature rupture of membranes,premature birth,fetal distress,postpartum hemorrhage,macrosomia and cesarean delivery of experimental group were significantly higher than that in control group（P〈0.05）.Conclusion GDM has a relatively large effect on pregnancy outcomes,causing serious complications of maternal and infant.Therefore,glucose metabolism during pregnancy should be surprised closely and education should be conducted to improve maternal and neonatal outcomes.

关 键 词：妊娠期糖尿病 血糖 葡萄糖耐量试验 分娩结局 

分 类 号：R714.256[医药卫生—妇产科学]