炎症、胰岛素抵抗与糖尿病的中药治疗  

Inflammation,Insulin Resistance and Traditional Chinese Medicine Treatment of Diabetes Mellitus

作　　者：聂绪强[1] 张丹丹[1] 张涵[1] 

机构地区：[1]遵义医学院药学院,贵州遵义563000

出　　处：《中国药学杂志》2017年第1期1-7,共7页Chinese Pharmaceutical Journal

基　　金：国家自然科学基金资助项目(81560712);贵州省科技重大专项(黔科合重大专项字[2015]6010);贵州省科技厅联合基金项目(黔科合LH字[2014]7566);贵州省教育厅自然科学研究项目(黔教合KY字[2015]439);遵义市红花岗区科技项目(遵红科合社字[2015]06)

摘　　要：现在越来越多的证据表明低度炎症与心脏病,2型糖尿病,阿尔茨海默病以及一些癌症相关。胰岛素抵抗和胰岛素分泌不足是糖尿病发病的两个关键因素,而炎症因子可引起胰岛素抵抗、胰岛素分泌不足。近来研究表明,中药的复方、单体或者提取物对糖尿病、胰岛素抵抗及其炎症也有独特的作用。笔者对炎症、胰岛素抵抗的致病机理及糖尿病的中药治疗做一综述。Low grade inflammation has recently emerged as a common underlying cause of many chronic diseases. Heart disease, type 2 diabetes, Alzheimer＇s disease and many types of cancer have all been associated with chronic inflammation. Diabetes is a group of metabolic diseases characterized by hyperglycemia resulting from defects in insulin secretion, insulin action, or both. Insulin resistance is a key component in the development of diabetes mellitus which is caused by inflammation, and throughout the whole process of diabetes. In recent years, research on traditional Chinese medicine treatment of diabetes has got lots of achievements, and makes a further analysis about insulin resistance of diabetic, while has profound significance in the treatment of diabetes in the future. Insulin resistance can be improved with Chinese herb medicine using compound, single herbal drug and its extracts. This review focuses on the pathogenesis of inflammation and insulin resistance, and the effects of Chinese herb medicine on insulin resistance in diabetes.

关 键 词：症 胰岛素抵抗 糖尿病 中药 

分 类 号：R965[医药卫生—药理学]